Cigarette smoking is the single most important risk factor for the development of
cardiovascular and pulmonary diseases (CVPD). Although cigarette smoking has been in …

This document was written with the intent to be a complete reference at the time of
publication on the topic of managing hypertension in the elderly. Given the length of the …

For cancers to develop, sustain and spread, the appropriation of key homeostatic
physiological systems that influence cell growth, migration and death, as well as …

Vascular inflammation contributes to cardiovascular diseases such as aortic aneurysm and
dissection. However, the precise inflammatory pathways involved have not been clearly …

Abstract Monocyte chemoattractant/chemotactic protein-1 (MCP-1), a member of the CC
chemokine family, is one of the key chemokines that regulate migration and tissue infiltration …

Smoking is the only modifiable risk factor that is associated with the development, expansion
and rupture of abdominal aortic aneurysm (AAA). However, the causative link between …

Objective—Obesity promotes macrophage infiltration into adipose tissue and is associated
with increases in several cardiovascular diseases. Infusion of angiotensin II (AngII) to mice …

OBJECTIVES: To evaluate whether either angiotensin converting enzyme (ACE) inhibitors
or other classes of antihypertensive drug attenuate or increase growth rates of small …

The AT 1 receptor, a major effector of the renin-angiotensin system, has been extensively
studied in the context of cardiovascular and renal disease. Moreover, angiotensin receptor …

BACKGROUND: A modest (41%) reduction in abdominal aortic aneurysm (AAA) growth rate
is likely to delay AAA-related events (surgery or rupture) by 5 years, making the notion of …