Endoplasmic reticulum stress impedes regulated secretion by governing key exocytotic and granulogenic molecular switches
M Mukherjee, C Mukherjee, V Ghosh… - Journal of Cell …, 2024 - journals.biologists.com
Dense core vesicles (DCVs) and synaptic vesicles are specialised secretory vesicles in
neurons and neuroendocrine cells, and abnormal release of their cargo is associated with …
neurons and neuroendocrine cells, and abnormal release of their cargo is associated with …
Recent advances in extracellular vesicles in amyotrophic lateral sclerosis and emergent perspectives
GJM Afonso, C Cavaleiro, J Valero, SI Mota, E Ferreiro - Cells, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a severe and incurable neurodegenerative disease
characterized by the progressive death of motor neurons, leading to paralysis and death. It is …
characterized by the progressive death of motor neurons, leading to paralysis and death. It is …
Extracellular vesicles from human plasma for biomarkers discovery: Impact of anticoagulants and isolation techniques
V Bettio, E Mazzucco, A Antona, S Cracas, M Varalda… - Plos one, 2023 - journals.plos.org
Extracellular vesicles (EVs) isolated from plasma are increasingly recognized as promising
circulating biomarkers for disease discovery and progression, as well as for therapeutic drug …
circulating biomarkers for disease discovery and progression, as well as for therapeutic drug …
Exosomal noncoding RNAs in central nervous system diseases: biological functions and potential clinical applications
ZY Wang, ZJ Wen, HM Xu, Y Zhang… - Frontiers in Molecular …, 2022 - frontiersin.org
Central nervous system (CNS) disease is a general term for a series of complex and diverse
diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), multiple sclerosis …
diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), multiple sclerosis …
Extracellular vesicles—the next frontier in endocrinology
A Das Gupta, N Krawczynska, ER Nelson - Endocrinology, 2021 - academic.oup.com
Extracellular vesicles (EVs), including exosomes, are emerging as important carriers of
signals in normal and pathological physiology. As EVs are a long-range communication or …
signals in normal and pathological physiology. As EVs are a long-range communication or …
[HTML][HTML] The neurotoxicity of vesicles secreted by ALS patient myotubes is specific to exosome-like and not larger subtypes
E Anakor, V Milla, O Connolly, C Martinat, PF Pradat… - Cells, 2022 - mdpi.com
Extracellular vesicles can mediate communication between tissues, affecting the
physiological conditions of recipient cells. They are increasingly investigated in Amyotrophic …
physiological conditions of recipient cells. They are increasingly investigated in Amyotrophic …
[HTML][HTML] Genomic and transcriptomic advances in amyotrophic lateral sclerosis
M Rizzuti, L Sali, V Melzi, S Scarcella… - Ageing Research …, 2023 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder and the most common
motor neuron disease. ALS shows substantial clinical and molecular heterogeneity. In vitro …
motor neuron disease. ALS shows substantial clinical and molecular heterogeneity. In vitro …
Efficient management of energy consumption of electric vehicles using machine learning—A systematic and comprehensive survey
Electric vehicles are growing in popularity as a form of transportation, but are still underused
for several reasons, such as their relatively low range and the high costs associated with …
for several reasons, such as their relatively low range and the high costs associated with …
Targeting amyotrophic lateral sclerosis by neutralizing seeding-competent TDP-43 in CSF
M Audrain, AL Egesipe, N Tentillier, L Font… - Brain …, 2023 - academic.oup.com
In amyotrophic lateral sclerosis, a disease driven by abnormal transactive response DNA-
binding protein of 43 kDa aggregation, CSF may contain pathological species of transactive …
binding protein of 43 kDa aggregation, CSF may contain pathological species of transactive …
Bioengineering extracellular vesicles as novel nanocarriers towards brain disorders
J Wu, L Ma, D Sun, X Zhang, J Cui, Y Du, Y Guo… - Nano Research, 2023 - Springer
Despite noteworthy technological progress and promising preclinical trials, brain disorders
are still the leading causes of death globally. Extracellular vesicles (EVs), nano-/micro-sized …
are still the leading causes of death globally. Extracellular vesicles (EVs), nano-/micro-sized …