Signalling mechanisms driving homeostatic and inflammatory effects of interleukin-15 on tissue lymphocytes
N Skariah, OJ James, M Swamy - Discovery Immunology, 2024 - academic.oup.com
There is an intriguing dichotomy in the function of cytokine interleukin-15—at low levels, it is
required for the homeostasis of the immune system, yet when it is upregulated in response …
required for the homeostasis of the immune system, yet when it is upregulated in response …
The roles of different forms of IL-15 in human melanoma progression
S Di Matteo, E Munari, PF Fiore, S Santopolo… - Frontiers in …, 2023 - frontiersin.org
Background Melanoma is a lethal skin cancer, and the risk of developing it is increased by
exposure to ultraviolet (UV) radiation. The production of cytokines such as interleukin-15 (IL …
exposure to ultraviolet (UV) radiation. The production of cytokines such as interleukin-15 (IL …
Interleukin-15 is a hair follicle immune privilege guardian
T Suzuki, J Chéret, FS Dinelli, A Rajabi-Estarabadi… - Journal of …, 2024 - Elsevier
The autoimmunity-promoting cytokine, Interleukin-15 (IL-15), is often claimed to be a key
pathogenic cytokine in alopecia areata (AA). Yet, rhIL-15 promotes human hair follicle (HF) …
pathogenic cytokine in alopecia areata (AA). Yet, rhIL-15 promotes human hair follicle (HF) …
Profibrogenic role of IL-15 through IL-15 receptor alpha-mediated trans-presentation in the carbon tetrachloride-induced liver fibrosis model
Background Inflammatory cytokines play key pathogenic roles in liver fibrosis. IL-15 is a
proinflammatory cytokine produced by myeloid cells. IL-15 promotes pathogenesis of …
proinflammatory cytokine produced by myeloid cells. IL-15 promotes pathogenesis of …
IL-15 prolongs anagen, stimulates proliferation, and suppresses apoptosis in the hair matrix of human scalp hair follicles
T Suzuki, F Scala, DL Demetrius… - The Journal of …, 2024 - pubmed.ncbi.nlm.nih.gov
IL-15 Prolongs Anagen, Stimulates Proliferation, and Suppresses Apoptosis in the Hair Matrix of
Human Scalp Hair Follicles IL-15 Prolongs Anagen, Stimulates Proliferation, and Suppresses …
Human Scalp Hair Follicles IL-15 Prolongs Anagen, Stimulates Proliferation, and Suppresses …
[HTML][HTML] Interleukins: pathophysiological role in acute pancreatitis
Acute pancreatitis (AP) is a common inflammatory state characterized by a clinical course
that can lead to serious local and extrapancreatic organ malfunction and failure. Interleukins …
that can lead to serious local and extrapancreatic organ malfunction and failure. Interleukins …