Epidemiology and prevention of prostate cancer

G Gandaglia, R Leni, F Bray, N Fleshner… - European urology …, 2021 - Elsevier
Abstract Context Worldwide, prostate cancer (PCa) represents the second most common
solid tumor in men. Objective To assess the geographical distribution of PCa …

FOXM1: A small fox that makes more tracks for cancer progression and metastasis

MA Khan, P Khan, A Ahmad, M Fatima… - Seminars in Cancer …, 2023 - Elsevier
Transcription factors (TFs) are indispensable for the modulation of various signaling
pathways associated with normal cell homeostasis and disease conditions. Among cancer …

[HTML][HTML] Prostate cancer incidence and mortality: global status and temporal trends in 89 countries from 2000 to 2019

L Wang, B Lu, M He, Y Wang, Z Wang… - Frontiers in public health, 2022 - frontiersin.org
Aims To evaluate current status of prostate cancer incidence and mortality worldwide, and
compare the global trends of incidence and mortality in the past two decades and in the …

Engineering the MoS2/MXene Heterostructure for Precise and Noninvasive Diagnosis of Prostate Cancer with Clinical Specimens

S Xie, X Fei, J Wang, YC Zhu, J Liu, X Du… - Advanced …, 2023 - Wiley Online Library
High‐throughput metabolic fingerprinting has been deemed one of the most promising
strategies for addressing the high false positive rate of prostate cancer (PCa) diagnosis in …

METTL14 promotes prostate tumorigenesis by inhibiting THBS1 via an m6A-YTHDF2-dependent mechanism

Y Wang, J Chen, WQ Gao, R Yang - Cell death discovery, 2022 - nature.com
Abstract N6-methyladenine (m6A) is the most predominant RNA modification, which has
been shown to be related to many types of cancers. However, understanding of its role in …

CircRNA circ_0006156 inhibits the metastasis of prostate cancer by blocking the ubiquitination of S100A9

Y Zhang, F Liu, Y Feng, X Xu, Y Wang, S Zhu… - Cancer Gene …, 2022 - nature.com
Circular RNAs (circRNAs) have been demonstrated to play vital roles in cancer development
and progression. However, studies on the association between circRNAs and prostate …

Biomarkers of aggressive prostate cancer at diagnosis

BE Boehm, ME York, G Petrovics, I Kohaar… - International Journal of …, 2023 - mdpi.com
In the United States, prostate cancer (CaP) remains the second leading cause of cancer
deaths in men. CaP is predominantly indolent at diagnosis, with a small fraction (25–30%) …

From omics to multi-omics approaches for in-depth analysis of the molecular mechanisms of prostate cancer

E Nevedomskaya, B Haendler - International Journal of Molecular …, 2022 - mdpi.com
Cancer arises following alterations at different cellular levels, including genetic and
epigenetic modifications, transcription and translation dysregulation, as well as metabolic …

Identification of cancer-associated fibroblasts subtypes in prostate cancer

J Pan, Z Ma, B Liu, H Qian, X Shao, J Liu… - Frontiers in …, 2023 - frontiersin.org
Introduction Cancer-associated fibroblasts (CAFs) are one of the most abundant cell types in
tumor microenvironment. However, the phenotypic and functional heterogeneities among …

[HTML][HTML] Explainable artificial intelligence to predict and identify prostate cancer tissue by gene expression

A Ramírez-Mena, E Andrés-León… - Computer Methods and …, 2023 - Elsevier
Abstract Background and Objective: Prostate cancer is one of the most prevalent forms of
cancer in men worldwide. Traditional screening strategies such as serum PSA levels, which …