Bromelain supplementation and inflammatory markers: A systematic review of clinical trials

IC Pereira, EES Vieira, LR de Oliveira Torres… - Clinical Nutrition …, 2023 - Elsevier
Background and aims The inflammatory process is a response mechanism to any stressor
agent. Emerging novel therapeutic options derived mainly from natural products such as …

Nature-derived ingredients as sustainable alternatives for tenderizing meat and meat products: an updated review

EG Anaduaka, CC Chibuogwu, AL Ezugwu… - Food …, 2023 - Taylor & Francis
Tenderness is one of the most desirable meat qualities and a significant determinant of
consumers' preference. Estimating/achieving optimal tenderness are not straightforward …

Hepatoprotective and neuroprotective effect of taxifolin on hepatic encephalopathy in rats

U Okkay, I Ferah Okkay, B Cicek, IC Aydin… - Metabolic Brain …, 2022 - Springer
This study was planned to assess the potential protective effects of taxifolin against
thioacetamide-induced hepatic encephalopathy and subsequently to portray its behavioural …

Sustainable eutectic mixture-based ultrasound assisted multifaceted valorisation of pineapple waste for bromelain and bioethanol production

HB Balaraman, S Umasekar, KS Rajmohan… - Sustainable Chemistry …, 2022 - Elsevier
A large number of pineapple residues like peels, leaves and stems generated during
processing remains underutilized. The current investigation provides one-pot task-specific …

Exploring the Therapeutic Potential of Bromelain: Applications, Benefits, and Mechanisms

U Kansakar, V Trimarco, MV Manzi, E Cervi, P Mone… - Nutrients, 2024 - mdpi.com
Bromelain is a mixture of proteolytic enzymes primarily extracted from the fruit and stem of
the pineapple plant (Ananas comosus). It has a long history of traditional medicinal use in …

Bromelain mitigates liver fibrosis via targeting hepatic stellate cells in vitro and in vivo

AA Sayed, AM Soliman, M Marzouk, FF Mohammed… - Tissue and Cell, 2023 - Elsevier
Various therapeutic approaches are conducted for regression of liver fibrosis and prevent
possible further carcinogenic transformation. This study was aimed to assess the …

Arbutin abrogates cisplatin-induced hepatotoxicity via upregulating Nrf2/HO-1 and suppressing genotoxicity, NF-κB/iNOS/TNF-α and caspase-3/Bax/Bcl2 signaling …

IF Okkay, A Famurewa, C Bayram, U Okkay… - Toxicology …, 2024 - academic.oup.com
Background: Cisplatin is a potent anticancer agent widely employed in chemotherapy.
However, cisplatin leads to toxicity on non-targeted healthy organs, including the liver. We …

Gastroprotective effects of bromelain on indomethacin-induced gastric ulcer in rats

B Danışman, B Çiçek, S Yıldırım… - GSC Biological and …, 2023 - gsconlinepress.com
Gastric ulcer is one of the most common diseases of the gastrointestinal system and some of
its complications are the main causes of morbidity and mortality. Bromelain (BRM), a …

In vitro neuroprotective effects of allicin on Alzheimer's disease model of neuroblastoma cell line

U Okkay, IF Okkay - Journal of Surgery and Medicine, 2022 - dergipark.org.tr
Background/Aim: Alzheimer's disease is a progressive disorder that causes atrophy and
neuronal death in the brain. Currently, there is not any effective therapy for Alzheimer's …

Therapeutic Potential of Bacopa monnieri L. in Sciatic Nerve Ligation: Modulation of Regeneration and Oxidative Stress

Z Al-yaqoobi, Ö Altunlu, F Burul, E Topatan… - … Hayvanları Bilimi ve … - dergipark.org.tr
Bacopa monnieri L. is a plant known for its neuroprotective properties with positive effects on
neuronal regeneration and synaptic activity. In this study, the effects of Bacopa monnieri L …