Biomarkers for dementia in Latin American countries: Gaps and opportunities

MA Parra, P Orellana, T Leon, CG Victoria… - Alzheimer's & …, 2023 - Wiley Online Library
Limited knowledge on dementia biomarkers in Latin American and Caribbean (LAC)
countries remains a serious barrier. Here, we reported a survey to explore the ongoing work …

A genome-wide association study identifies multiple loci for variation in human ear morphology

K Adhikari, G Reales, AJP Smith, E Konka… - Nature …, 2015 - nature.com
Here we report a genome-wide association study for non-pathological pinna morphology in
over 5,000 Latin Americans. We find genome-wide significant association at seven genomic …

Human genetic admixture

KL Korunes, A Goldberg - PLoS genetics, 2021 - journals.plos.org
Throughout human history, large-scale migrations have facilitated the formation of
populations with ancestry from multiple previously separated populations. This process …

[HTML][HTML] Origin and health status of first-generation Africans from early colonial Mexico

R Barquera, TC Lamnidis, AK Lankapalli, A Kocher… - Current Biology, 2020 - cell.com
The forced relocation of several thousand Africans during Mexico's historic period has so far
been documented mostly through archival sources, which provide only sparse detail on their …

A positively selected FBN1 missense variant reduces height in Peruvian individuals

S Asgari, Y Luo, A Akbari, GM Belbin, X Li, DN Harris… - Nature, 2020 - nature.com
On average, Peruvian individuals are among the shortest in the world. Here we show that
Native American ancestry is associated with reduced height in an ethnically diverse group of …

Ancestry, admixture and fitness in Colombian genomes

L Rishishwar, AB Conley, CH Wigington, L Wang… - Scientific reports, 2015 - nature.com
The human dimension of the Columbian Exchange entailed substantial genetic admixture
between ancestral source populations from Africa, the Americas and Europe, which had …

Admixture in latin america

K Adhikari, J Mendoza-Revilla… - Current opinion in …, 2016 - Elsevier
Latin Americans arguably represent the largest recently admixed populations in the world.
This reflects a history of massive settlement by immigrants (mostly Europeans and Africans) …

Investigating mitonuclear interactions in human admixed populations

AA Zaidi, KD Makova - Nature ecology & evolution, 2019 - nature.com
To function properly, mitochondria utilize products of 37 mitochondrial and> 1,000 nuclear
genes, which should be compatible with each other. Discordance between mitochondrial …

The genetic diversity of the Americas

K Adhikari, JC Chacón-Duque… - Annual review of …, 2017 - annualreviews.org
The history of the Americas involved the encounter of millions of Native Americans,
Europeans, and Africans. A variable admixture of these three continental groups has taken …

Novel genetic loci affecting facial shape variation in humans

Z Xiong, G Dankova, LJ Howe, MK Lee, PG Hysi… - elife, 2019 - elifesciences.org
The human face represents a combined set of highly heritable phenotypes, but knowledge
on its genetic architecture remains limited, despite the relevance for various fields. A series …