[HTML][HTML] Latin American Dialysis and Transplant Registry: Experience and contributions to end-stage renal disease epidemiology

AM Cusumano, GJ Rosa-Diez… - World journal of …, 2016 - ncbi.nlm.nih.gov
Abstract In 2015, 634387 million people (9% of the world's population) resided in Latin
America (LA), with half of those populating Brazil and Mexico. The LA Dialysis and …

Anthropological genetics perspectives on the transatlantic slave trade

C Fortes-Lima, P Verdu - Human Molecular Genetics, 2021 - academic.oup.com
Abstract During the Trans-Atlantic Slave Trade (TAST), around twelve million Africans were
enslaved and forcibly moved from Africa to the Americas and Europe, durably influencing …

Dominantly inherited Alzheimer's disease in Latin America: Genetic heterogeneity and clinical phenotypes

JJ Llibre‐Guerra, Y Li, RF Allegri… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction A growing number of dominantly inherited Alzheimer's disease (DIAD) cases
have become known in Latin American (LatAm) in recent years. However, questions …

Ancestry effects on type 2 diabetes genetic risk inference in Hispanic/Latino populations

AT Chande, L Rishishwar, AB Conley… - BMC Medical …, 2020 - Springer
Abstract Background Hispanic/Latino (HL) populations bear a disproportionately high
burden of type 2 diabetes (T2D). The ability to predict T2D genetic risk using polygenic risk …

The articulation of genomics, mestizaje, and indigenous identities in Chile: a case study of the social implications of genomic research in light of current research …

CP Silva, C De la Fuente Castro… - Frontiers in …, 2022 - frontiersin.org
Genomic research has contributed significantly to our understanding of present-day human
biological diversity, health, and disease. However, at the same time, genomic research has …

Genetic cancer risk assessment for breast cancer in Latin America

Y Chavarri-Guerra, KR Blazer… - Revista de investigación …, 2017 - medigraphic.com
ABSTRACT In Latin America, breast cancer is the most common malignancy in women, and
limited available data suggest that up to 15% of all breast cancer cases in the region are …

Variation in dental morphology and inference of continental ancestry in admixed Latin Americans

M Delgado, LM Ramírez, K Adhikari… - American Journal of …, 2019 - Wiley Online Library
Objectives To investigate the variation in dental nonmetric traits and to evaluate the utility of
this variation for inferring genetic ancestry proportions in a sample of admixed Latin …

Understanding (mis) classification trends of Latin Americans in Fordisc 3.1: Incorporating cranial morphology, microgeographic origin, and admixture proportions for …

CE Hughes, B Dudzik… - Journal of Forensic …, 2019 - Wiley Online Library
Assigning correct population affinity to a skeleton can contribute important information to an
investigation—yet recent work highlights high error rates when classifying Latinos with a …

Clozapine metabolism is associated with absolute neutrophil count in individuals with treatment-resistant schizophrenia

IR Willcocks, SE Legge, M Nalmpanti… - Frontiers in …, 2021 - frontiersin.org
Up to one-third of those with schizophrenia fail to respond to standard antipsychotics and
are considered to have treatment-resistant schizophrenia, a condition for which clozapine is …

Heterogeneity in the distribution of 159 drug-response related SNPs in world populations and their genetic relatedness

T Ahsan, NJ Urmi, AA Sajib - PLoS One, 2020 - journals.plos.org
Interethnic variability in drug response arises from genetic differences associated with drug
metabolism, action and transport. These genetic variations can affect drug efficacy as well as …