[HTML][HTML] Current research status of anti-cancer peptides: Mechanism of action, production, and clinical applications

RK Chinnadurai, N Khan, GK Meghwanshi… - Biomedicine & …, 2023 - Elsevier
The escalating rate of cancer cases, together with treatment deficiencies and long-term side
effects of currently used cancer drugs, has made this disease a global burden of the 21st …

[HTML][HTML] Time to kill and time to heal: the multifaceted role of lactoferrin and lactoferricin in host defense

A Ohradanova-Repic, R Praženicová, L Gebetsberger… - Pharmaceutics, 2023 - mdpi.com
Lactoferrin is an iron-binding glycoprotein present in most human exocrine fluids,
particularly breast milk. Lactoferrin is also released from neutrophil granules, and its …

[HTML][HTML] Biomedical and nutritional applications of lactoferrin

C Coccolini, E Berselli, C Blanco-Llamero… - International Journal of …, 2023 - Springer
Lactoferrin (Lf) is a glycoprotein belonging to the transferrin family, which can be found in
mammalian milk. It was first isolated from bovine milk in the 1930s, and later in the 1960s, it …

[HTML][HTML] Lactoferrin: Antimicrobial impacts, genomic guardian, therapeutic uses and clinical significance for humans and animals

ME Abd El-Hack, SA Abdelnour, M Kamal… - Biomedicine & …, 2023 - Elsevier
Lactoferrin (LF) is a protein found in several bodily fluids, such as milk. This protein has a
diverse range of functions and is evolutionarily conserved. Lactoferrin is a multifunction …

[HTML][HTML] Enhanced Cellular Uptake and Transport of Bovine lactoferrin using pectin-and Chitosan-modified solid lipid nanoparticles

X Yao, C Bunt, M Liu, SY Quek, J Shaw, J Cornish… - Pharmaceutics, 2023 - mdpi.com
Aim: The aim of this project is to use pectin-and chitosan-modified solid lipid nanoparticles
for bovine lactoferrin to enhance its cellular uptake and transport. Methods: Solid lipid …

[HTML][HTML] Production of Bioactive Porcine Lactoferrin through a Novel Glucose-Inducible Expression System in Pichia pastoris: Unveiling Antimicrobial and Anticancer …

CC Yen, PY Wu, H Ou-Yang, HL Chen… - International Journal of …, 2024 - mdpi.com
Lactoferrin (LF) stands as one of the extensively investigated iron-binding glycoproteins
within milk, exhibiting diverse biological functionalities. The global demand for LF has …

[HTML][HTML] Lactoferrin, a Great Wall of host-defence?

J Wang, N Yang, HJ Vogel - Biometals, 2023 - Springer
Lactoferrin (Lf) is a multifunctional iron-binding glycoprotein that is specifically produced by
exocrine glands and it is also expressed at high levels in neutrophils in mammals. Since this …

[HTML][HTML] Lactoferricin B Combined with Antibiotics Exhibits Leukemic Selectivity and Antimicrobial Activity

JJ Lica, K Gucwa, M Heldt, A Stupak, N Maciejewska… - Molecules, 2024 - mdpi.com
The fusion of penetrating peptides (PPs), eg, cell penetration peptides (CPPs) or
antimicrobial peptides (AMPs), together with antimicrobial agents is an expanding research …

Fabrication of docetaxel-loaded hyaluronic acid coated zeolitic imidazolate framework‑8 as an effective treatment for leukaemia cancer cells and its apoptosis …

S Wu, H Li, D Su, N Lu - Journal of Experimental Nanoscience, 2024 - Taylor & Francis
Drug delivery systems (DDSs) have been developed to carry an appropriate payload into
the tumour's area, accomplishing the goals of minimising potential bodily harm and …

[HTML][HTML] Lactoferrin and Activated Protein C: Potential Role in Prevention of Cancer Progression and Recurrence

N Akhtar, AK Wani, M Jan, S Sinha… - … Journal of Molecular …, 2023 - ncbi.nlm.nih.gov
Existing therapeutic interventions for controlling cancer are limited and associated with side
effects. Furthermore, the recurrence of cancer poses a significant challenge to the cure of …