Development of de-novo coronavirus 3-chymotrypsin-like protease (3CLpro) inhibitors since COVID-19 outbreak: A strategy to tackle challenges of persistent virus …

L Tian, T Qiang, X Yang, Y Gao, X Zhai, K Kang… - European Journal of …, 2023 - Elsevier
Although no longer a public health emergency of international concern, COVID-19 remains
a persistent and critical health concern. The development of effective antiviral drugs could …

Inhalable hybrid nanovaccines with virus-biomimetic structure boost protective immune responses against SARS-CoV-2 variants

S Wang, P Ding, L Shen, D Fan, H Cheng… - Journal of …, 2024 - Springer
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with different
antigenic variants, has posed a significant threat to public health. It is urgent to develop …

Induction of protective immune responses at respiratory mucosal sites

SC Park, MJ Wiest, V Yan, PT Wong… - Human Vaccines & …, 2024 - Taylor & Francis
Many pathogens enter the host through mucosal sites. Thus, interfering with pathogen entry
through local neutralization at mucosal sites therefore is an effective strategy for preventing …

A multi-epitope/CXCL11 prime/pull coronavirus mucosal vaccine boosts the frequency and the function of lung-resident memory CD4+ and CD8+ T cells and …

L Zayou, S Prakash, NR Dhanushkodi… - Journal of …, 2023 - Am Soc Microbiol
The pandemic of the coronavirus disease 2019 (COVID-19) has created the largest global
health crisis in almost a century. Low frequencies of functional SARS-CoV-2-specific CD4+ …

Blended BA. 5 infection within 8 days after a boosted bivalent mRNA vaccination strengthens and lengthens the host immunity

M Huang, T Cui, S Liu, X Su, Y Wang… - Journal of Medical …, 2024 - Wiley Online Library
The impact of SARS‐CoV‐2 infection shortly after vaccination on vaccine‐induced immunity
is unknown, which is also one of the concerns for some vaccinees during the pandemic …

Nanoparticle-Mediated Mucosal Vaccination: Harnessing Nucleic Acids for Immune Enhancement

W Hussain, S Chaman, HN Koser, SM Aun, Z Bibi… - Current …, 2024 - Springer
Recent advancements in in vitro transcribed mRNA (IVT-mRNA) vaccine manufacturing
have attracted considerable interest as advanced methods for combating viral infections …

Recent Advancement in Self Emulsifing Drug Delivery System

VL Bist, A Faruk - Journal for Research in Applied Sciences and …, 2023 - jrasb.com
Every day, researchers make new attempts to identify neurotherapeutics, but few of them
make it to clinical trials. The main cause is their low bioavailability, which is connected to low …

Adsorption of Favipiravir as Drug of Coronavirus Disease on Cu-Si52, Cu-C52, Cu-Al26N26, Cu-SiNT (6, 0), Cu-CNT (6, 0) and Cu-AlNT (6, 0)

F Altalbawy, M Singh, K Phaninder Vinay, RA Bakr… - Silicon, 2024 - Springer
This work wants to investigate the potential of Cu-Si 52, Cu-C 52, Cu-Al 26 N 26, Cu-doped
nanotubes (6, 0) to adsorb and deliver the Favipiravir as COVID-19 drug by DSD-PBEPBE …

Оценка эффективности и безопасности топических интерферонов альфа-2b в форме геля и мази для профилактики острых респираторных заболеваний в …

КВ Козлов, КВ Жданов, ОВ Мальцев… - Журнал …, 2024 - journal.niidi.ru
Аннотация Ежегодная заболеваемость острыми респираторными заболеваниями
остается ведущей в структуре инфекционной патологии в Российской Федерации …

Advances in Drug Delivery Systems: A Mini-Review

LM Shaker, AA Al-Amiery… - Al-Ameed Journal for …, 2023 - ajmrhs.alameed.edu.iq
Drug delivery systems (DDS) refer to technologies designed to improve the safety and
efficacy of drugs by controlling their release, absorption, and distribution in the body. DDS …