In this study, we aim to assess the phytomedicinal potential of perillyl alcohol (PA), a dietary
monoterpenoid, in a unilateral 6-hydroxydopamine (6-OHDA) lesion rat model of …

Parkinson's disease (PD) drugs treat symptoms without inhibiting progression. In recent
years, finding novel therapeutic medications that can halt disease progression has become …

MicroRNAs are reportedly involved in the pathogenesis of neurodegenerative diseases,
including Parkinson's disease and multiple system atrophy. We previously identified 7 …

Various immunologic and inflammatory factors are contributed to pathogenesis of
Parkinson's disease (PD). High mobility group box-1 (HMGB1) is a protein that plays certain …

Aging is an inevitable physiological challenge occurring in organisms over time, and is also
the most important risk factor of neurodegenerative diseases. In this study, we observed …

Hyperactivation of microglia, the resident innate immune cells of the central nervous system,
exacerbates various neurodegenerative disorders, including Parkinson's disease (PD) …

Parkinson's disease (PD) is the second most common age-related neurodegenerative
disease in the world, and synuclein is closely related to the onset and progression of PD …

Parkinson's Disease (PD) is characterized by classic motor symptoms related to movement,
but PD patients can experience symptoms associated with impaired autonomic function …

Background Parkinson's disease (PD) is the second most prevalent neurodegenerative
disorder and it arises when most of the dopaminergic neurons of substantia nigra region die …

Parkinson's disease (PD) is a progressive neurological disorder characterized by
degeneration of dopaminergic neurons in the substantia nigra. However, although 200 …