Advances in the molecular landscape of lung cancer brain metastasis

VGP Souza, RP de Araújo, MR Santesso, AL Seneda… - Cancers, 2023 - mdpi.com
Simple Summary Patients with lung cancer have high rates of brain metastasis (BM).
Despite available therapies, patient prognosis is poor. Studies have shown genetic …

Exosomal miR-4466 from nicotine-activated neutrophils promotes tumor cell stemness and metabolism in lung cancer metastasis

A Tyagi, SY Wu, S Sharma, K Wu, D Zhao… - Oncogene, 2022 - nature.com
Smoking is associated with lung cancer and has a profound impact on tumor immunity.
Nicotine, the addictive and non-carcinogenic smoke component, influences various brain …

Imaging of brain metastasis in non-small-cell lung cancer: indications, protocols, diagnosis, post-therapy imaging, and implications regarding management

N Chakrabarty, A Mahajan, V Patil, V Noronha… - Clinical Radiology, 2023 - Elsevier
Increased survival (due to the use of targeted therapies based on genomic profiling) has
resulted in the increased incidence of brain metastasis during the course of disease, and …

Preoperative MRI‐based radiomics of brain metastasis to assess T790M resistance mutation after EGFR‐TKI treatment in NSCLC

Y Fan, L He, H Yang, Y Wang, J Su… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Preoperative assessment of the acquired resistance T790M mutation in patients
with metastatic non‐small cell lung cancer (NSCLC) based on brain metastasis (BM) is …

LINC01806 mediated by STAT1 promotes cell proliferation, migration, invasion, and stemness in non-small cell lung cancer through Notch signaling by miR-4428 …

S Huang, S Liang, J Huang, P Luo, D Mo… - Cancer Cell …, 2022 - Springer
Background Non-small cell lung cancer (NSCLC), the most primary lung cancer subtype,
threatens human health globally. Long non-coding RNAs (lncRNAs) have been uncovered …

Establishment of a prognostic risk prediction modelfor non-small cell lung cancer patients with brainmetastases: a retrospective study

F Hou, Y Hou, XD Sun, HM Jiang, M Zhang, C Liu… - PeerJ, 2023 - peerj.com
Background Patients with non-small cell lung cancer (NSCLC) who develop brain
metastases (BM) have a poor prognosis. This study aimed to construct a clinical prediction …

[HTML][HTML] GABA (A) Receptor Activation Drives GABARAP–Nix Mediated Autophagy to Radiation-Sensitize Primary and Brain-Metastatic Lung Adenocarcinoma Tumors

D Bhattacharya, R Barrile, DK Toukam, VS Gawali… - Cancers, 2024 - mdpi.com
Simple Summary Non-small cell lung cancer (NSCLC) accounts for 80–85% of primary lung
cancers. Radiation therapy is widely used to treat both primary NSCLC and lung cancer that …

[HTML][HTML] Survival and prognostic factors in patients undergoing the resection of solitary brain metastasis from non-small cell lung cancer: a retrospective cohort study

M Xu, K Song, Z Zhou, Z Yu, Y Lv… - Journal of Thoracic …, 2022 - ncbi.nlm.nih.gov
Background Neurosurgery is the standard of care for resectable solitary brain metastasis
(BM) from non-small cell lung cancer (NSCLC), but still with a poor outcome. Postoperative …

Performance status improvement and advances in systemic treatment after brain metastases resection: a retrospective single-center cohort study of non-small cell lung …

K Hosoya, H Ozasa, M Tanji, H Yoshida, H Ajimizu… - BMC cancer, 2024 - Springer
Abstract Background Brain metastasis (BrM) is prevalent among patients with NSCLC, and
surgical resection of BrM constitutes a promising treatment strategy for local management …

Expression and Clinical Significance of Serum Krüppel‐Like Factor 7 (KLF7) in NSCLC Patients

H Song, J Sun, Z Xu, X Liu, N Liu - … and Mathematical Methods …, 2022 - Wiley Online Library
Nonsmall cell lung cancer (NSCLC) is a serious threat to the life and health of patients with
high incidence rate and mortality. The present research was to assess the relationship …