Purpose Laryngopharyngeal reflux disease (LPRD) is a general term for the reflux of
gastroduodenal contents into the laryngopharynx, oropharynx and even the nasopharynx …

In recent decades, dysregulation of proteases and atypical proteolysis have become
increasingly recognized as important hallmarks of cancer, driving community-wide efforts to …

Abstract The effects of Naphthol Yellow S (NYS) on the structure and activity of pepsin were
carried out using ultraviolet–visible (UV–Vis) spectroscopy, intrinsic fluorescence …

Background & Aims Gastric reflux may lead to chronic mucosal inflammation and contribute
to development of laryngeal malignancies, although there is controversy over this …

Laryngopharyngeal reflux, a variant of gastroesophageal reflux disease, has been
considered a risk factor in the development of hypopharyngeal cancer. Bile acids are …

Background Laryngopharyngeal reflux (LPR), with its increasing morbidity, is attracting
considerable attention. In recent years, the causal role between LPR and laryngeal …

Squamous cell carcinoma (SCC) is a malignant epithelial tumor showing evidence of
squamous differentiation. It is the most common malignancy of the larynx, with several …

Objective Laryngopharyngeal reflux (LPR) is a common affliction that contributes to
laryngeal inflammation, symptoms that impact quality of life, and life‐threatening illnesses …

Gastroesophageal reflux disease (GERD) significantly impacts patient quality of life and is a
major risk factor for the development of Barrett's esophagus (BE) and esophageal …

Laryngeal carcinogenesis is a multistep process, characterized by an accumulation of
genetic changes associated with architectural and cytologic alterations, ranging from …