Progress continues to be made in our understanding of pepsin-mediated damage with
implications for novel therapeutic strategies. Salivary pepsin diagnostics continue to garner …

The upper aerodigestive tract (UAT) is the first line of defense against environmental
stresses such as antigens, microbes, inhalants, foods, etc., and mucins, intracellular …

Laryngopharyngeal reflux (LPR) is a common defect among laryngological and phoniatric
patients. Although LPR is categorized as a superficial gastroesophageal reflux disease …

Gastric cancer (GC) is still an extremely severe health issue with high mortality due to the
lacking of effective biomarkers. In this study, we aimed to investigate the alterations of …

Purpose Gastroesophageal reflux disease (GERD) has been associated with head and neck
cancer (HNC), including laryngeal and pharyngeal anatomical sites. A systematic review …

Airway reflux is implicated in the pathophysiology of a wide range of adult and pediatric
upper and lower airway diseases. However, the diagnosis of proximal reflux–associated …

Objectives To identify the bile acids in the saliva of patients with and without
gastroesophageal reflux disease (GERD), and evaluate their effect on tooth surface. Design …

Gastroesophageal reflux disease (GERD) significantly impacts patient quality of life and is a
major risk factor for the development of Barrett's esophagus (BE) and esophageal …

Saliva is a complex physiologic fluid that contains an abundance of biological analytes, or
biomarkers. Recent research has shown that these biomarkers may be able to convey the …

Abstract MCM2, MCM3 and MCM7 are minichromosome maintenance proteins found in
dividing cells and they play a role in DNA synthesis. Increased MCM expression level is …