In recent years, neutrophils have attracted increasing attention because of their cancer-
promoting effects. An elevated neutrophil-to-lymphocyte ratio is considered a prognostic …

The mutational landscape of colorectal cancer (CRC) does not enable predictions to be
made about the survival of patients or their response to therapy. Instead, studying the …

Liver metastases are commonly detected in a range of malignancies including colorectal
cancer (CRC), pancreatic cancer, melanoma, lung cancer and breast cancer, although CRC …

Transforming growth factor-beta (TGF-β) signaling is one of the important cellular pathways
that play key roles for tissue maintenance. In particular, it is important in the context of …

Neutrophils act as the first line of defense against invading pathogens. Although traditionally
considered in context of their antimicrobial effector functions, the importance of tumor …

Fusobacterium nucleatum is implicated in accelerating colorectal cancer (CRC) and is found
within metastatic CRC cells in patient biopsies. Here, we found that bacterial invasion of …

Colorectal cancer (CRC) has the second highest mortality rate among all cancers
worldwide. Surgery, chemotherapy, radiotherapy, molecular targeting and other treatment …

The number of colorectal cancer (CRC) patients is increasing worldwide. Accumulating
evidence has shown that the tumor microenvironment (TME), including macrophages …

Cancer cachexia (CC) is a multifactorial syndrome in patients with advanced cancer
characterized by weight loss via skeletal-muscle and adipose-tissue atrophy, catabolic …

Colorectal cancer (CRC) is one of the most common cancers worldwide, which ranks third in
terms of incidence and the second leading cause of cancer-related mortality. Metabolic …