Extracellular vesicles (EVs) are biological nanoparticles that promote intercellular
communication by delivering bioactive cargo over short and long distances. Short-distance …

Emerging data indicate that neurological complications occur as a consequence of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The blood–brain barrier …

It is unclear whether severe acute respiratory syndrome coronavirus 2, which causes
coronavirus disease 2019, can enter the brain. Severe acute respiratory syndrome …

Extracellular vesicles can cross the blood–brain barrier (BBB), but little is known about
passage. Here, we used multiple-time regression analysis to examine the ability of 10 …

Central nervous system (CNS) barriers predominantly mediate the immune-privileged status
of the brain, and are also important regulators of neuroimmune communication. It is …

Individuals living with HIV who are optimally treated with combination antiretroviral therapy
(cART) can now lead an extended life. In spite of this remarkable survival benefit from viral …

Brain endothelial cells are unique among endothelial cells in that they express apical
junctional complexes, including tight junctions, which quite resemble epithelial tight …

HIV-associated dementia (HAD) is an important complication of the central nervous system
in patients who are infected with HIV-1. Although the incidence of HAD has markedly …

Disruption of the tight junctions (TJs) of the blood–brain barrier (BBB) is a hallmark of many
CNS pathologies, including stroke, HIV encephalitis, Alzheimer's disease, multiple sclerosis …

All organisms with a complex nervous system have a well-developed blood-central nervous
system barrier. In the vertebrates the central nervous system (CNS) lies behind the …