Potential benefits of antioxidant phytochemicals in type 2 diabetes

A Arabshomali, S Bazzazzadehgan, F Mahdi… - Molecules, 2023 - mdpi.com
The clinical relationship between diabetes and inflammation is well established. Evidence
clearly indicates that disrupting oxidant-antioxidant equilibrium and elevated lipid …

Platelets in Renal Disease

D Gomchok, RL Ge, T Wuren - International Journal of Molecular …, 2023 - mdpi.com
Kidney disease is a major global health concern, affecting millions of people. Nephrologists
have shown interest in platelets because of coagulation disorders caused by renal diseases …

LC-MS/MS-based serum metabolomics and transcriptome analyses for the mechanism of augmented renal clearance

Y Wang, Y Luo, S Yang, M Jiang, Y Chu - International Journal of …, 2023 - mdpi.com
Augmented Renal Clearance (ARC) refers to the increased renal clearance of circulating
solute in critically ill patients. In this study, the analytical research method of transcriptomics …

Mannose binding lectin-associated serine protease-1 is a novel contributor to myocardial ischemia/reperfusion injury

S Zhang, L Yang, S Guo, F Hu, D Cheng, J Sun… - International Journal of …, 2023 - Elsevier
Background The lectin pathway has been demonstrated to play a critical role in the
pathological process of myocardial ischemia/reperfusion injury (IRI). Mannose-binding lectin …

[HTML][HTML] Autoantibodies from patients with kidney allograft vasculopathy stimulate a proinflammatory switch in endothelial cells and monocytes mediated via GPCR …

G Moll, C Luecht, MA Gyamfi, DLM da Fonseca… - Frontiers in …, 2023 - frontiersin.org
Non-HLA-directed regulatory autoantibodies (RABs) are known to target G-protein coupled
receptors (GPCRs) and thereby contribute to kidney transplant vasculopathy and failure …

The role of thromboinflammation in acute kidney injury among patients with septic coagulopathy

T Iba, J Helms, CL Maier, M Levi, E Scarlatescu… - Journal of Thrombosis …, 2024 - Elsevier
Inflammation and coagulation are critical self-defense mechanisms for mitigating infection
that can nonetheless induce tissue injury and organ dysfunction. In severe cases, like …

Proteinase-activated Receptor 2: Springboard of Tumors

D Vetvicka, P Suhaj, T Olejar, L Sivak… - Anticancer …, 2024 - ar.iiarjournals.org
Proteinase-activated receptors (PARs) were discovered more than 25 years ago and since
then, their role in cancer has been under investigation. Research has primarily focused on …

Harnessing the Power of Polyphenols: A New Frontier in Disease Prevention and Therapy

M El Oirdi - Pharmaceuticals, 2024 - mdpi.com
There are a wide variety of phytochemicals collectively known as polyphenols. Their
structural diversity results in a broad range of characteristics and biological effects …

Comprehensive analysis of ceRNA network and immune cell infiltration pattern of autophagy related genes in IgA nephropathy

H Zhang, H Lu, B Zhan, H Shi, B Shui - Kidney & blood pressure …, 2024 - karger.com
Abstract Introduction: IgA nephropathy (IgAN) is a prevalent worldwide glomerular disease
with a complex pathophysiology that has significant economic implications. Despite the lack …

Targeting Oxidative Stress May Contribute to Improving the Inflammatory State and Glycemic Index of Glucose Control in Type 2 Diabetes

A Arabshomali, S Bazzazzadehgan, F Mahdi… - 2023 - preprints.org
The clinical relationship between diabetes and inflammation is well-established. Various
branches of science independently have confirmed that disrupting oxidant-antioxidant …