[HTML][HTML] Nrf2-mediated anti-inflammatory polarization of macrophages as therapeutic targets for osteoarthritis
L Wang, C He - Frontiers in immunology, 2022 - frontiersin.org
Macrophages are the most abundant immune cells within the synovial joints, and also the
main innate immune effector cells triggering the initial inflammatory responses in the …
main innate immune effector cells triggering the initial inflammatory responses in the …
The roles of macrophage polarization in the host immune response to sepsis
X Chen, Y Liu, Y Gao, S Shou, Y Chai - International immunopharmacology, 2021 - Elsevier
Sepsis is a life-threatening clinical syndrome caused by infection. Its pathogenesis is
complex and entails coagulation dysfunction, inflammation, and immune disorders …
complex and entails coagulation dysfunction, inflammation, and immune disorders …
Understanding the mysterious M2 macrophage through activation markers and effector mechanisms
T Rőszer - Mediators of inflammation, 2015 - Wiley Online Library
The alternatively activated or M2 macrophages are immune cells with high phenotypic
heterogeneity and are governing functions at the interface of immunity, tissue homeostasis …
heterogeneity and are governing functions at the interface of immunity, tissue homeostasis …
[HTML][HTML] Anti-inflammatory microRNAs and their potential for inflammatory diseases treatment
A Tahamtan, M Teymoori-Rad, B Nakstad… - Frontiers in …, 2018 - frontiersin.org
Inflammation is a complicated biological and pathophysiological cascade of responses to
infections and injuries, and inflammatory mechanisms are closely related to many diseases …
infections and injuries, and inflammatory mechanisms are closely related to many diseases …
Macrophage polarization and allergic asthma
Allergic asthma is associated with airway inflammation and airway hyperresponsiveness.
Macrophage polarization has been shown to have a profound impact on asthma …
Macrophage polarization has been shown to have a profound impact on asthma …
MiRNA-mediated macrophage polarization and its potential role in the regulation of inflammatory response
Monocytes and macrophages are important components of the immune system, specialized
in either removing pathogens as part of innate immunity or contributing to adaptive immunity …
in either removing pathogens as part of innate immunity or contributing to adaptive immunity …
Macrophage polarization and meta-inflammation
Chronic overnutrition and obesity induces low-grade inflammation throughout the body.
Termed “meta-inflammation,” this chronic state of inflammation is mediated by macrophages …
Termed “meta-inflammation,” this chronic state of inflammation is mediated by macrophages …
[HTML][HTML] Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as …
W Ren, J Hou, C Yang, H Wang, S Wu, Y Wu… - Journal of Experimental …, 2019 - Springer
Objective To investigate the lung cancer-promoting mechanism of mesenchymal stem cell-
secreted extracellular vesicles (MSC-EV). Methods EV were isolated from culture media of …
secreted extracellular vesicles (MSC-EV). Methods EV were isolated from culture media of …
[HTML][HTML] A narrative review of tumor-associated macrophages in lung cancer: regulation of macrophage polarization and therapeutic implications
SS Sedighzadeh, AP Khoshbin, S Razi… - … lung cancer research, 2021 - ncbi.nlm.nih.gov
Lung cancer is the deadliest malignancy worldwide. An inflammatory microenvironment is a
key factor contributing to lung tumor progression. Tumor-Associated Macrophages (TAMs) …
key factor contributing to lung tumor progression. Tumor-Associated Macrophages (TAMs) …
CSF1R‐and SHP2‐inhibitor‐loaded nanoparticles enhance cytotoxic activity and phagocytosis in tumor‐associated macrophages
Immune modulation of macrophages has emerged as an attractive approach for anti‐cancer
therapy. However, there are two main challenges in successfully utilizing macrophages for …
therapy. However, there are two main challenges in successfully utilizing macrophages for …