Abstract Introduction Recently, Nrf2/HO-1 has received extensive attention as the main
regulatory pathway of intracellular defense against oxidative stress and is considered an …

Estrogen receptors (ERs) regulate multiple complex physiological processes in humans.
Abnormal ER signaling may result in various disorders, including reproductive system …

Estrogen is an essential sex steroid hormone that functions primarily in female reproductive
system, as well as in a variety of tissues and organs with pleiotropic effects, such as in …

Context The effect of kaempferol, a regulator of oestrogen receptors, on atherosclerosis (AS)
and the underlying mechanism is elusive. Objective To explore the effect and mechanism of …

Background: Hypertension grows into a serious public health problem among young adults,
linking to a set of life-threatening cardiovascular diseases (CVDs). Young adults are not well …

Cardiovascular disease (CVD) is the leading cause of death globally for men and women.
Premenopausal women have a lower incidence of hypertension and other cardiovascular …

Flavonoids isolated from medicinal herbs have been utilized as valuable health-care agents
due to their virous biological applications. Alpinetin is a natural flavonoid that emerges in …

The pathogenesis of obesity-associated cardiovascular diseases begins long prior to the
presentation of a cardiovascular event. In both men and women, cardiovascular events, and …

Transgender women are assigned male at birth but identified as women. The incidence of
gender dysphoria is estimated to be around 1% of the population. Gender dysphoria may be …

Bisphenols, endocrine disrupting chemicals, have frequently been used for producing food
packaging materials. The best-known member, bisphenol A (BPA), has been linked to …