Effect of dehydroepiandrosterone on atherosclerosis in postmenopausal women

S Zhang, J Zhou, L Li, X Pan, J Lin, C Li… - BioScience …, 2021 - jstage.jst.go.jp
In China, cardiovascular disease (CVD) has surpassed malignant tumours to become the
disease with the highest mortality rate, and atherosclerosis (AS) is an important pathological …

Novel targets for a combination of mechanical unloading with pharmacotherapy in advanced heart failure

A Jedrzejewska, A Braczko, A Kawecka… - International Journal of …, 2022 - mdpi.com
LVAD therapy is an effective rescue in acute and especially chronic cardiac failure. In
several scenarios, it provides a platform for regeneration and sustained myocardial …

The cardiotonic steroid marinobufagenin is a predictor of increased left ventricular mass in obesity: The African-PREDICT study

M Strauss-Kruger, R Kruger, W Smith… - Nutrients, 2020 - mdpi.com
The endogenous Na+/K+-ATPase inhibitor, marinobufagenin (MBG), strongly associates
with salt intake and a greater left ventricular mass index (LVMi) in humans and was shown to …

Coronary artery event-free or resilient familial hypercholesterolemia: what's in a name?

SST Zadeh, DC Chan, P Mata… - Current Opinion in …, 2024 - journals.lww.com
A group of HeFH patients, referred as resilient FH, can survive to advance ages without
experiencing any ASCVD events. Several key contributors to the event-fee CAD in HeFH …

The emerging role of noncoding RNAs in the PI3K/AKT/mTOR signalling pathway in breast cancer

MH Abu-Alghayth, FR Khan, TM Belali… - … -Research and Practice, 2024 - Elsevier
Breast cancer persists as a major problem for the world's healthcare, thus it is essential to
fully understand the complex molecular processes that cause its growth and development …

Vitamin D Deficiency Reduces Vascular Reactivity of Coronary Arterioles in Male Rats

Z Fontányi, RE Sziva, É Pál, L Hadjadj… - Current Issues in …, 2021 - mdpi.com
Background: Vitamin D deficiency (VDD) may be considered an independent cardiovascular
(CV) risk factor, and it is well known that CV risk is higher in males. Our goal was to …

Estrogen Oppositely Regulates Pulmonary Hypertension via METTL3/PFKFB3 Under Normoxia and Hypoxia

X Li, J Wang, Y Chen, P Li, H Wen, X Xu… - American Journal of …, 2024 - atsjournals.org
Despite extensive investigation into estrogen's role in pulmonary hypertension (PH)
development, its effects-whether beneficial or detrimental-remains contentious. This study …

Maternal postnatal early overfeeding induces sex-related cardiac dysfunction and alters sexually hormones levels in young offspring

LA Ferreira, MD Ferreira-Junior, KJV Amaral… - The Journal of …, 2022 - Elsevier
Postnatal early overfeeding (PO) is a risk factor for cardiometabolic disorders. However,
remains unknown the cardiac effects in the second generation from postnatal overfed dams …

Gender-Related Difference in Skin Oxygenation in Young Patients with Uncomplicated Type 1 Diabetes

J Neubauer-Geryk, M Myśliwiec, L Bieniaszewski - Biomedicines, 2024 - mdpi.com
Gender, through genetic, epigenetic and hormonal regulation, is an important modifier of the
physiological mechanisms and clinical course of diseases. In diabetes mellitus, there are …

Predicting phase-I metabolism of piceatannol: an in silico study

RK Rajan, M Engels, M Ramanathan - In Silico Pharmacology, 2024 - Springer
Piceatannol is a natural compound found in plants and can be derived from resveratrol.
While resveratrol has been extensively researched for its effects and how the body …