[HTML][HTML] MiRNA-29b and miRNA-497 modulate the expression of Carboxypeptidase X member 2, a candidate gene associated with Left ventricular hypertrophy

J Subrova, K Böhme, A Gillespie, M Orphal… - International journal of …, 2022 - mdpi.com
Left ventricular hypertrophy (LVH) is a major risk factor for adverse cardiovascular events.
Recently, a novel candidate gene encoding the carboxypeptidase X member 2 (CPXM2) …

[HTML][HTML] Chronic GPR30 agonist therapy causes regression in a male mouse model of progressive heart failure: insights into cellular mechanisms

X Zhang, T Li, HJ Cheng, H Wang, CM Ferrario… - Life …, 2021 - ncbi.nlm.nih.gov
Aims: G protein-coupled estrogen receptor 30 (GPR30) activation by its agonist, G1, exhibits
beneficial actions in female with heart failure (HF). Recent evidence indicates its …

[HTML][HTML] Sacubitril/valsartan improves sexual function and fibrosis of the clitoral and vaginal tissues in female spontaneously hypertensive rats

C Zhuang, G Yi, W Wang, R Sun, M Qi… - Journal of …, 2022 - journals.lww.com
Female sexual dysfunction is common in hypertension. The effects of sacubitril/valsartan
(SAC/VAL) as a potential therapy for hypertension and heart failure have not been studied in …

[PDF][PDF] 血浆致动脉硬化指数评价急性ST 段抬高型心肌梗死的临床价值

张同昌, 李海山, 陈敏, 张峰, 张静 - 临床急诊杂志, 2023 - lcjzen.whuhzzs.com
血浆致动脉硬化指数评价急性ST段抬高型心肌梗死的临床价值∗ Page 1 2023年 临床急诊杂志
24卷7期 JClinEmerg(China) 引用本文:张同昌,李海山,陈敏,等.血浆致动脉硬化指数评价急性 …

创伤性脊髓损伤微循环中的靶向药物治疗

R Wang, J Bai - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
创伤性脊髓损伤主要表现为感觉, 运动, 自主神经功能障碍, 严重影响日常生活能力.
这些不良结果与脊髓损伤机制复杂, 中枢神经元的再生能力有限以及创伤性损伤形成的抑制环境 …

[HTML][HTML] Toward the effective bioengineering of a pathological tissue for cardiovascular disease modeling: old strategies and new frontiers for prevention, diagnosis …

L Iop - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Cardiovascular diseases (CVDs) still represent the primary cause of mortality worldwide.
Preclinical modeling by recapitulating human pathophysiology is fundamental to advance …

Epigenetic programming of human disease and aging

NA Rivero-Segura, D Castro-Morales… - Epigenetics in Human …, 2024 - Elsevier
As many authors state, aging has been conceptualized as a biological process that leads to
declining function and increases the susceptibility to age-related diseases such as cancer …

[HTML][HTML] The cardiometabolic benefits of exercise in postmenopausal women

SG Chrysant - The Journal of Clinical Hypertension, 2020 - ncbi.nlm.nih.gov
Menopause in women is associated with significant cardiometabolic changes, which
increase the risk for cardiovascular diseases and premature death. Most of these …

Timing of percutaneous coronary intervention and risk of new‐onset acute ischemic stroke in non‐ST elevation myocardial infarction: A retrospective cohort study …

B Shi, X Ma, C Ye, R Yan, S Fu, K Wang… - Health Science …, 2024 - Wiley Online Library
Abstract Background and Aims For patients with high‐risk non‐ST elevation myocardial
infarction (NSTEMI), current guidelines recommend an early invasive strategy within 24 h …

In vitro cadmium exposure induces structural damage and endothelial dysfunction in female rat aorta

LCC Sepulchro Mulher, RP Simões, KA Rossi… - BioMetals, 2023 - Springer
Cadmium is a heavy metal that is widespread in the environment and has been described
as a metalloestrogen and a cardiovascular risk factor. Experimental studies conducted in …