Ventricular arrhythmia without structural heart disease is an arrhythmic disorder that occurs
in structurally normal heart and no transient or reversible arrhythmia factors, such as …

Membranes consisting of phospholipid bilayers are an essential constituent of eukaryotic
cells and their compartments. The alteration of their composition, structure, and morphology …

Cardiomyopathies (CMPs) are a heterogeneous group of myocardial diseases accountable
for the majority of cases of heart failure (HF) and/or sudden cardiac death (SCD) worldwide …

Sudden death is a rare event in the pediatric population but with a social shock due to its
presentation as the first symptom in previously healthy children. Comprehensive autopsy in …

Brugada syndrome (BrS) is a hereditary disorder, characterized by a specific
electrocardiogram pattern and highly related to an increased risk of sudden cardiac death …

Cardiac voltage‐gated ion channels (VGICs) play critical roles in mediating cardiac
electrophysiological signals, such as action potentials, to maintain normal heart excitability …

Ajmaline is an anti-arrhythmic drug that is used to unmask the type-1 Brugada syndrome
(BrS) electrocardiogram pattern to diagnose the syndrome. Thus, the disease is defined at …

Background The lack of disease-modifying drugs is one of the major unmet needs in
patients with heart failure (HF). Peptides are highly selective molecules with the potential to …

L-type calcium channels (LTCCs), the largest subfamily of voltage-gated calcium channels
(VGCCs), are the main channels for Ca2+ influx during extracellular excitation. LTCCs are …

Brugada 波是一种特殊的心电图形, 表现为右束支阻滞, 右胸导联ST 段抬高和T 波倒置“三联征”,
可导致心律失常和心脏性猝死. 既往认为Brugada 波与遗传学, 电生理学, 神经崤假说等有关 …