Molecular characterization of membrane steroid receptors in hormone-sensitive cancers

M Masi, M Racchi, C Travelli, E Corsini, E Buoso - Cells, 2021 - mdpi.com
Cancer is one of the most common causes of death worldwide, and its development is a
result of the complex interaction of genetic factors, environmental cues, and aging. Hormone …

[HTML][HTML] Exploring the physiological role of the G protein-coupled estrogen receptor (GPER) and its associations with human diseases

M Żabińska, K Wiśniewska, G Węgrzyn… - …, 2024 - Elsevier
Estrogen is a group of hormones that collaborate with the nervous system to impact the
overall well-being of all genders. It influences many processes, including those occurring in …

GPER: An Estrogen Receptor Key in Metastasis and Tumoral Microenvironments

AC Tirado-Garibay, EA Falcón-Ruiz… - International Journal of …, 2023 - mdpi.com
Estrogens and their role in cancer are well-studied, and some cancer types are classified in
terms of their response to them. In recent years, a G protein-coupled estrogen receptor …

Comparative G-protein-coupled estrogen receptor (GPER) systems in diabetic and cancer conditions: A review

A Muhammad, GE Forcados, AP Yusuf, MB Abubakar… - Molecules, 2022 - mdpi.com
For many patients, diabetes Mellitus and Malignancy are frequently encountered
comorbidities. Diabetes affects approximately 10.5% of the global population, while …

Vaccination of Gilthead Seabream After Continuous Xenoestrogen Oral Exposure Enhances the Gut Endobolome and Immune Status via GPER1

P Castejón, I Cabas, V Gómez, E Chaves-Pozo… - Frontiers in …, 2021 - frontiersin.org
In fish culture settings, the exogenous input of steroids is a matter of concern. Recently, we
unveiled that in the gilthead seabream (Sparus aurata), the G protein-coupled estrogen …

GPER agonist G-1 disrupts tubulin dynamics and potentiates temozolomide to impair glioblastoma cell proliferation

A Hirtz, N Lebourdais, F Rech, Y Bailly, A Vaginay… - Cells, 2021 - mdpi.com
Glioblastoma (GBM) is the most common brain tumor in adults, which is very aggressive,
with a very poor prognosis that affects men twice as much as women, suggesting that female …

Assessment of G protein-coupled oestrogen receptor expression in normal and neoplastic human tissues using a novel rabbit monoclonal antibody

M Bubb, ASL Beyer, P Dasgupta, D Kaemmerer… - International journal of …, 2022 - mdpi.com
In addition to the classical oestrogen receptors, ERα and ERβ, a G protein-coupled
oestrogen receptor (GPER) has been identified that primarily mediates the rapid, non …

A review of the functions of G protein-coupled estrogen receptor 1 in vascular and neurological aging

S Yang, Z Yin, G Zhu - European Journal of Pharmacology, 2021 - Elsevier
Aging-related diseases, especially vascular and neurological disorders cause huge
economic burden. How to delay vascular and neurological aging is one of the …

Paradigm Shift: A Comprehensive Review of Ovarian Cancer Management in an Era of Advancements

V Tavares, IS Marques, IG Melo, J Assis… - International Journal of …, 2024 - mdpi.com
Ovarian cancer (OC) is the female genital malignancy with the highest lethality. Patients
present a poor prognosis mainly due to the late clinical presentation allied with the common …

[HTML][HTML] Research progress of estrogen receptor in ovarian cancer

M Zhang, H Xu, Y Zhang, Z Li, W Meng, J Xia… - Clinical and …, 2023 - imrpress.com
Objective: This review aims to provide some theoretical guidance for the precise treatment of
ovarian cancer and the development of estrogen-related drugs. Mechanism: Ovarian cancer …