Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

Cancer stemness, defined as the self-renewal and tumor-initiation potential of cancer stem
cells (CSCs), is a cancer biology property featuring activation of CSC signaling networks …

Diverse functions of proteins, including synthesis, catalysis, and signaling, result from their
highly variable amino acid sequences. The technology allowing for direct analysis of protein …

Cancer stem cells (CSCs), which have the potential for self-renewal, differentiation and de-
differentiation, undergo epigenetic, epithelial-mesenchymal, immunological and metabolic …

Prostate cancer is initially responsive to androgen deprivation, but the effectiveness of
androgen receptor (AR) inhibitors in recurrent disease is variable. Biopsy of bone …

Colorectal cancer is one of the most common cancers worldwide with high mortality. Distant
metastasis and relapse are major causes of patient death. Cancer stem cells (CSCs) play a …

Hepatocellular carcinoma (HCC) is a highly lethal cancer, with increasing worldwide
incidence, that is mainly associated with chronic hepatitis B virus (HBV) and/or hepatitis C …

Fibroblast growth factors (FGFs) are involved in a variety of cellular processes, such as
stemness, proliferation, anti‐apoptosis, drug resistance, and angiogenesis. Here, FGF …

Abstract β‑catenin/CTNNB1 is an intracellular scaffold protein that interacts with adhesion
molecules (E‑cadherin/CDH1, N‑cadherin/CDH2, VE‑cadherin/CDH5 and α‑catenins) …

Chromosomal rearrangements are initiating events in acute lymphoblastic leukaemia (ALL).
Here using RNA sequencing of 560 ALL cases, we identify rearrangements between …