Chemotherapy is an effortless and frequently used approach in cancer therapy. However, in
most cases, it can only prolong life expectancy and does not guarantee a complete cure …

The integrity of the basal stem cell layer is critical for epithelial homoeostasis. In this paper,
we review the expression of oral mucosal stem cell markers (OM-SCMs) in oral submucous …

Cancers in the gastrointestinal system account for a large proportion of malignancies and
cancer-related deaths with gastric cancer and colorectal cancer being the most common …

Aberrant activation of wingless (Wnt) signaling is involved in the pathogenesis of various
cancers. Recent studies suggested a role of Wnt signaling in gliomas, the most common …

Chondroitin sulfate proteoglycan 4 (CSPG4), also known as High Molecular Weight-
Melanoma Associated Antigen, is a cell surface proteoglycan which has been recently …

Recent studies have revealed that bacteria target stem cells for long-term survival in a
Drosophila model. However, in mammalian models, little is known about bacterial infection …

Differentiation therapy is a novel approach to eradicate cancer stem cells (CSCs), including
head and neck squamous carcinoma CSC (HNSC CSC). All-trans-retinoic acid (ATRA) is a …

The recent publication of the TCGA Kidney Renal Clear Cell Carcinoma (KIRC) project has
provided an immense wealth and breadth of data providing an invaluable tool for …

Reprogramming of nuclei allows the dedifferentiation of differentiated cells. Somatic cells
can undergo epigenetic modifications and reprogramming through their fusion with …

The Wnt/β-catenin signaling pathway is pathologically activated in cholangiocarcinoma
(CCA). Here, we determined the expression profile as well as biological role of activated …