Tuberous sclerosis (also known as tuberous sclerosis complex [TSC]) is a multisystem
genetic disorder that affects almost every organ in the body. Mutations in the TSC1 or TSC2 …

Tuberous sclerosis complex (TSC) involves abnormalities of the skin (hypomelanotic
macules, confetti skin lesions, facial angiofibromas, shagreen patches, fibrous cephalic …

Background Tuberous sclerosis complex (TSC) is a rare autosomal dominant genetic
disorder. Many gaps remain in the understanding of TSC because of the complexity in …

Tuberous sclerosis complex (TSC) is associated with a wide range of behavioral,
psychiatric, intellectual, academic, neuropsychological, and psychosocial difficulties, which …

OBJECTIVES: Tuberous sclerosis complex (TSC) is a neurocutaneous genetic disorder with
a high prevalence of epilepsy and neurodevelopmental disorders. TSC can be challenging …

Introduction: Individuals with Tuberous Sclerosis Complex (TSC) are at increased risk of
developing both epilepsy and autism spectrum disorder (ASD), but the relationship between …

Autism spectrum disorder (ASD) is highly prevalent in subjects with Tuberous Sclerosis
Complex (TSC), but we are not still able to reliably predict which infants will develop ASD …

Autism spectrum disorders and epilepsies are heterogeneous human disorders that have
miscellaneous etiologies and pathophysiology. There is considerable risk of frequent …

Objective Tuberous sclerosis complex (TSC) is a rare disease with a high risk of epilepsy
and cognitive impairment in children. Ketogenic diet (KD) therapy has been consistently …

Background Tuberous sclerosis complex (TSC) is a rare autosomal dominant genetic
disorder associated with mutations in TSC1 and TSC2 genes, upregulation of mammalian …