[HTML][HTML] Microneedles in drug delivery: progress and challenges

M Avcil, A Çelik - Micromachines, 2021 - mdpi.com
In recent years, an innovative transdermal delivery technology has attracted great interest for
its ability to distribute therapeutics and cosmeceuticals for several applications, including …

[HTML][HTML] Bioinspired nanotopographical design of drug delivery systems

JA Finbloom, C Huynh, X Huang… - Nature Reviews …, 2023 - nature.com
Effective drug delivery is important in the treatment of various biomedical conditions, ranging
from autoimmune disorders to cancer and bacterial infections. Nanostructured systems can …

Polymeric long-acting drug delivery systems (LADDS) for treatment of chronic diseases: Inserts, patches, wafers, and implants

H Abdelkader, Z Fathalla, A Seyfoddin… - Advanced drug delivery …, 2021 - Elsevier
Non-oral long-acting drug delivery systems (LADDS) encompass a range of technologies for
precisely delivering drug molecules into target tissues either through the systemic circulation …

Albendazole nanocrystal-based dissolving microneedles with improved pharmacokinetic performance for enhanced treatment of cystic echinococcosis

AD Permana, AJ Paredes, FV Zanutto… - … Applied Materials & …, 2021 - ACS Publications
Cystic echinococcosis (CE) is a zoonosis caused by Echinococcus spp., affecting both
humans and animals' lives. Current treatment of CE by oral administration of albendazole …

[HTML][HTML] Pharmaceutical approaches on antimicrobial resistance: prospects and challenges

F Nainu, AD Permana, NJN Djide, QK Anjani… - Antibiotics, 2021 - mdpi.com
The rapid increase in pathogenic microorganisms with antimicrobial resistant profiles has
become a significant public health problem globally. The management of this issue using …

[HTML][HTML] Microneedles for efficient and precise drug delivery in cancer therapy

K Ganeson, AH Alias, V Murugaiyah, AAA Amirul… - Pharmaceutics, 2023 - mdpi.com
Cancer is the leading cause of death, acting as a global burden, severely impacting the
patients' quality of life and affecting the world economy despite the expansion of cumulative …

[HTML][HTML] Battle of the milky way: Lymphatic targeted drug delivery for pathogen eradication

A Taheri, KE Bremmell, P Joyce… - Journal of Controlled …, 2023 - Elsevier
Many viruses, bacteria, and parasites rely on the lymphatic system for survival, replication,
and dissemination. While conventional anti-infectives can combat infection-causing agents …

Enhancement in site-specific delivery of chloramphenicol using bacterially sensitive microparticle loaded into dissolving microneedle: potential for enhanced …

M Mudjahid, F Nainu, RN Utami, A Sam… - … Applied Materials & …, 2022 - ACS Publications
One of the biggest challenges in infectious disease treatment is the existence of bacterial
infections in underskin wound tissue, such as cellulitis. Compared to other treatments, it is …

[HTML][HTML] Natural products targeting inflammation-related metabolic disorders: A comprehensive review

F Nainu, A Frediansyah, SS Mamada, AD Permana… - Heliyon, 2023 - cell.com
Currently, the incidence of metabolic disorders is increasing, setting a challenge to global
health. With major advancement in the diagnostic tools and clinical procedures, much has …

Leveraging Lymphatic System Targeting in Systemic Lupus Erythematosus for Improved Clinical Outcomes

KT Babalola, M Arora, R Ganugula, SK Agarwal… - Pharmacological …, 2024 - ASPET
The role of advanced drug delivery strategies in drug repositioning and minimizing drug
attrition rates, when applied early in drug discovery, is poised to increase the translational …