Bile acids in intrahepatic cholestasis of pregnancy

M Majsterek, M Wierzchowska-Opoka, I Makosz… - Diagnostics, 2022 - mdpi.com
Intrahepatic cholestasis of pregnancy (ICP) is the most common, reversible, and closely
related to pregnancy condition characterized by elevated levels of bile acids (BAs) in blood …

Melatonin: the placental antioxidant and anti-inflammatory

TT Joseph, V Schuch, DJ Hossack… - Frontiers in …, 2024 - frontiersin.org
Melatonin (N-acetyl-5-methoxytryptamine) is an indolamine hormone with many
physiological and biological roles. Melatonin is an antioxidant, anti-inflammatory, free …

Placentas from Women with Late-Onset Preeclampsia Exhibit Increased Expression of the NLRP3 Inflammasome Machinery

LM Garcia-Puente, O Fraile-Martinez… - Biomolecules, 2023 - mdpi.com
Pre-eclampsia is a harmful and potentially lethal medical condition during pregnancy
clinically diagnosed by hypertension and commonly accompanied by proteinuria and …

The placentas of women who suffer an episode of psychosis during pregnancy have increased lipid peroxidation with evidence of ferroptosis

MA Ortega, O Fraile-Martinez, C García-Montero… - Biomolecules, 2023 - mdpi.com
Psychosis is a complex entity characterized by psychological, behavioral, and motor
alterations resulting in a loss of contact with reality. Although it is not common, pregnancy …

Unfolding the role of placental-derived Extracellular Vesicles in Pregnancy: From homeostasis to pathophysiology

MA Ortega, O Fraile-Martínez… - Frontiers in Cell and …, 2022 - frontiersin.org
The human placenta is a critical structure with multiple roles in pregnancy, including fetal
nutrition and support, immunological, mechanical and chemical barrier as well as an …

Irregular expression of cellular stress response markers in the placenta of women with chronic venous disease

C García-Montero, O Fraile-Martinez… - Antioxidants, 2022 - mdpi.com
Pregnancy comprises a period in a woman's life in which the circulatory system is subjected
to hemodynamical and biochemical changes. During this period, while restructuring blood …

Endothelial dysfunction in preterm infants: The hidden legacy of uteroplacental pathologies

GS Amelio, L Provitera, G Raffaeli, M Tripodi… - Frontiers in …, 2022 - frontiersin.org
Millions of infants are born prematurely every year worldwide. Prematurity, particularly at
lower gestational ages, is associated with high mortality and morbidity and is a significant …

Histopathological Clues of Enhanced Inflammation in the Placental Tissue of Women with Chronic Venous Disease in Lower Limbs during Pregnancy

MA Sánchez-Gil, O Fraile-Martinez… - Journal of Personalized …, 2024 - mdpi.com
It is estimated that approximately one in three women develop chronic venous disease
(CVD) during pregnancy, a broad spectrum of morphofunctional disorders affecting the …

Assessment of tissue expression of the oxytocin–vasopressin pathway in the placenta of women with a first-episode psychosis during pregnancy

MA Ortega, C García-Montero… - International Journal of …, 2023 - mdpi.com
Psychosis refers to a mental health condition characterized by a loss of touch with reality,
comprising delusions, hallucinations, disorganized thought, disorganized behavior …

[HTML][HTML] Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction

Y Zhang, J Liang, H Gu, T Du, P Xu, T Yu, Q He… - Ecotoxicology and …, 2023 - Elsevier
Ethylhexyl diphenyl phosphate (EHDPP) is one of the typical organophosphate flame
retardants (OPFRs) and has been widely detected in environmental media. Exposure to …