[HTML][HTML] Current approaches of nanomedicines in the market and various stage of clinical translation

X Shan, X Gong, J Li, J Wen, Y Li, Z Zhang - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Compared with traditional drug therapy, nanomedicines exhibit intriguing biological features
to increase therapeutic efficiency, reduce toxicity and achieve targeting delivery. This review …

Materials engineering strategies for cancer vaccine adjuvant development

X Zhang, B Yang, Q Ni, X Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Cancer vaccines have emerged as a powerful new tool for cancer immunotherapy.
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …

Bioorthogonal-activated in situ vaccine mediated by a COF-based catalytic platform for potent cancer immunotherapy

M Sun, Z Liu, L Wu, J Yang, J Ren… - Journal of the American …, 2023 - ACS Publications
Personalized tumor vaccines have become a promising modality for cancer immunotherapy.
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …

The use of RNA-based treatments in the field of cancer immunotherapy

M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

Tumor–antigen activated dendritic cell membrane-coated biomimetic nanoparticles with orchestrating immune responses promote therapeutic efficacy against glioma

X Ma, L Kuang, Y Yin, L Tang, Y Zhang, Q Fan… - ACS …, 2023 - ACS Publications
Immunotherapy has had a profound positive effect on certain types of cancer but has not
improved the outcomes of glioma because of the blood–brain barrier (BBB) and …

Hybrid nanomaterials for cancer immunotherapy

J Li, W Lu, Y Yang, R Xiang, Y Ling, C Yu… - Advanced …, 2023 - Wiley Online Library
Nano‐immunotherapy has been recognized as a highly promising strategy for cancer
treatment in recent decades, which combines nanotechnology and immunotherapy to …

Cancer vaccines as promising immuno-therapeutics: platforms and current progress

J Liu, M Fu, M Wang, D Wan, Y Wei, X Wei - Journal of Hematology & …, 2022 - Springer
Research on tumor immunotherapy has made tremendous progress in the past decades,
with numerous studies entering the clinical evaluation. The cancer vaccine is considered a …

Tumour circular RNAs elicit anti-tumour immunity by encoding cryptic peptides

D Huang, X Zhu, S Ye, J Zhang, J Liao, N Zhang… - Nature, 2024 - nature.com
Emerging data have shown that previously defined noncoding genomes might encode
peptides that bind human leukocyte antigen (HLA) as cryptic antigens to stimulate adaptive …

Impact of risk factors on early cancer evolution

CE Weeden, W Hill, EL Lim, E Grönroos, C Swanton - Cell, 2023 - cell.com
Recent identification of oncogenic cells within healthy tissues and the prevalence of indolent
cancers found incidentally at autopsies reveal a greater complexity in tumor initiation than …

mRNA vaccines for cancer immunotherapy

YL Vishweshwaraiah, NV Dokholyan - Frontiers in immunology, 2022 - frontiersin.org
Immunotherapy has emerged as a breakthrough strategy in cancer treatment. mRNA
vaccines are an attractive and powerful immunotherapeutic platform against cancer because …