Biomimetic and bioinspired nano‐platforms for cancer vaccine development

C Feng, P Tan, G Nie, M Zhu - Exploration, 2023 - Wiley Online Library
The advent of immunotherapy has revolutionized the treating modalities of cancer. Cancer
vaccine, aiming to harness the host immune system to induce a tumor‐specific killing effect …

[HTML][HTML] Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy

JR van Beijnum, EJM Huijbers, K van Loon… - Nature …, 2022 - nature.com
Anti-angiogenic cancer therapies possess immune-stimulatory properties by counteracting
pro-angiogenic molecular mechanisms. We report that tumor endothelial cells ubiquitously …

[HTML][HTML] Roles of exosomes in immunotherapy for solid cancers

C Lyu, H Sun, Z Sun, Y Liu, Q Wang - Cell Death & Disease, 2024 - nature.com
Although immunotherapy has made breakthrough progress, its efficacy in solid tumours
remains unsatisfactory. Exosomes are the main type of extracellular vesicles that can deliver …

[HTML][HTML] Advances in glioblastoma therapy: an update on current approaches

RS Angom, NMR Nakka, S Bhattacharya - Brain sciences, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is a primary malignant brain tumor characterized by a high
grade of malignancy and an extremely unfavorable prognosis. The current efficacy of …

Polymeric nanoparticle-based nanovaccines for cancer immunotherapy

Y Zhang, J Chen, L Shi, F Ma - Materials Horizons, 2023 - pubs.rsc.org
Therapeutic cancer vaccines, which are designed to amplify tumor-specific T cell responses,
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …

[HTML][HTML] Virus-like particles as preventive and therapeutic cancer vaccines

AL Tornesello, M Tagliamonte, FM Buonaguro… - Vaccines, 2022 - mdpi.com
Virus-like particles (VLPs) are self-assembled viral protein complexes that mimic the native
virus structure without being infectious. VLPs, similarly to wild type viruses, are able to …

Vitamin E enhances cancer immunotherapy by reinvigorating dendritic cells via targeting checkpoint SHP1

X Yuan, Y Duan, Y Xiao, K Sun, Y Qi, Y Zhang… - Cancer discovery, 2022 - AACR
Despite the popular use of dietary supplements during conventional cancer treatments, their
impacts on the efficacies of prevalent immunotherapies, including immune-checkpoint …

[HTML][HTML] Multifunctional nanomedicines-enabled chemodynamic-synergized multimodal tumor therapy via Fenton and Fenton-like reactions

H Gao, Z Cao, H Liu, L Chen, Y Bai, Q Wu, X Yu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Chemodynamic therapy (CDT) is well-known for using the tumor microenvironment to
activate the Fenton reaction or Fenton-like reaction to generate strong oxidative hydroxyl …

Enhanced Immunogenic Cell Death and Antigen Presentation via Engineered Bifidobacterium bifidum to Boost Chemo-immunotherapy

T He, L Wang, S Gou, L Lu, G Liu, K Wang, Y Yang… - ACS …, 2023 - ACS Publications
The immunogenic cell death (ICD) of tumor cells has aroused great interest in the field of
immunotherapy, mainly due to the production of plentiful tumor-associated antigens (TAAs) …

Biosynthetic neoantigen displayed on bacteria derived vesicles elicit systemic antitumour immunity

F Meng, L Li, Z Zhang, Z Lin, J Zhang… - Journal of …, 2022 - Wiley Online Library
Neoantigens derived from mutant proteins in tumour cells could elicit potent personalized
anti‐tumour immunity. Nevertheless, the layout of vaccine vehicle and synthesis of …