Biomimetic and bioinspired nano‐platforms for cancer vaccine development
The advent of immunotherapy has revolutionized the treating modalities of cancer. Cancer
vaccine, aiming to harness the host immune system to induce a tumor‐specific killing effect …
vaccine, aiming to harness the host immune system to induce a tumor‐specific killing effect …
[HTML][HTML] Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy
JR van Beijnum, EJM Huijbers, K van Loon… - Nature …, 2022 - nature.com
Anti-angiogenic cancer therapies possess immune-stimulatory properties by counteracting
pro-angiogenic molecular mechanisms. We report that tumor endothelial cells ubiquitously …
pro-angiogenic molecular mechanisms. We report that tumor endothelial cells ubiquitously …
[HTML][HTML] Roles of exosomes in immunotherapy for solid cancers
C Lyu, H Sun, Z Sun, Y Liu, Q Wang - Cell Death & Disease, 2024 - nature.com
Although immunotherapy has made breakthrough progress, its efficacy in solid tumours
remains unsatisfactory. Exosomes are the main type of extracellular vesicles that can deliver …
remains unsatisfactory. Exosomes are the main type of extracellular vesicles that can deliver …
[HTML][HTML] Advances in glioblastoma therapy: an update on current approaches
Glioblastoma multiforme (GBM) is a primary malignant brain tumor characterized by a high
grade of malignancy and an extremely unfavorable prognosis. The current efficacy of …
grade of malignancy and an extremely unfavorable prognosis. The current efficacy of …
Polymeric nanoparticle-based nanovaccines for cancer immunotherapy
Therapeutic cancer vaccines, which are designed to amplify tumor-specific T cell responses,
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …
[HTML][HTML] Virus-like particles as preventive and therapeutic cancer vaccines
Virus-like particles (VLPs) are self-assembled viral protein complexes that mimic the native
virus structure without being infectious. VLPs, similarly to wild type viruses, are able to …
virus structure without being infectious. VLPs, similarly to wild type viruses, are able to …
Vitamin E enhances cancer immunotherapy by reinvigorating dendritic cells via targeting checkpoint SHP1
Despite the popular use of dietary supplements during conventional cancer treatments, their
impacts on the efficacies of prevalent immunotherapies, including immune-checkpoint …
impacts on the efficacies of prevalent immunotherapies, including immune-checkpoint …
[HTML][HTML] Multifunctional nanomedicines-enabled chemodynamic-synergized multimodal tumor therapy via Fenton and Fenton-like reactions
H Gao, Z Cao, H Liu, L Chen, Y Bai, Q Wu, X Yu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Chemodynamic therapy (CDT) is well-known for using the tumor microenvironment to
activate the Fenton reaction or Fenton-like reaction to generate strong oxidative hydroxyl …
activate the Fenton reaction or Fenton-like reaction to generate strong oxidative hydroxyl …
Enhanced Immunogenic Cell Death and Antigen Presentation via Engineered Bifidobacterium bifidum to Boost Chemo-immunotherapy
T He, L Wang, S Gou, L Lu, G Liu, K Wang, Y Yang… - ACS …, 2023 - ACS Publications
The immunogenic cell death (ICD) of tumor cells has aroused great interest in the field of
immunotherapy, mainly due to the production of plentiful tumor-associated antigens (TAAs) …
immunotherapy, mainly due to the production of plentiful tumor-associated antigens (TAAs) …
Biosynthetic neoantigen displayed on bacteria derived vesicles elicit systemic antitumour immunity
F Meng, L Li, Z Zhang, Z Lin, J Zhang… - Journal of …, 2022 - Wiley Online Library
Neoantigens derived from mutant proteins in tumour cells could elicit potent personalized
anti‐tumour immunity. Nevertheless, the layout of vaccine vehicle and synthesis of …
anti‐tumour immunity. Nevertheless, the layout of vaccine vehicle and synthesis of …