The role of progesterone signaling in the pathogenesis of uterine leiomyoma

JJ Kim, EC Sefton - Molecular and cellular endocrinology, 2012 - Elsevier
Uterine leiomyomas are benign tumors that originate from the myometrium. Evidence points
to ovarian steroid hormones, in particular, progesterone as major promoters of leiomyoma …

Intrauterine device use among women with uterine fibroids: a systematic review

LB Zapata, MK Whiteman, NK Tepper, DJ Jamieson… - Contraception, 2010 - Elsevier
BACKGROUND: There are concerns that intrauterine device (IUD) use by women with
uterine fibroids might increase their uterine bleeding or risk for device expulsion. The …

Cancer risk in women using the levonorgestrel-releasing intrauterine system in Finland

T Soini, R Hurskainen, S Grénman… - Obstetrics & …, 2014 - journals.lww.com
OBJECTIVE: To examine the association between premenopausal use of the levonorgestrel-
releasing intrauterine system and cancer incidence in Finland with a special focus on …

Modifiable prognostic factors in uterine fibroid development: a systematic review of literature

AL Keizer, A Semmler, HS Kok… - Journal of Obstetrics …, 2024 - Taylor & Francis
Background Many risk factors in uterine fibroid development have been identified, but
women and their physicians are less aware of the influence of lifestyle on uterine fibroid …

Levonorgestrel-releasing intrauterine system use in premenopausal women with symptomatic uterine leiomyoma: a systematic review

W Jiang, Q Shen, M Chen, Y Wang, Q Zhou, X Zhu… - Steroids, 2014 - Elsevier
A systematic review is done to determine the efficacy and safety of levonorgestrel-releasing
intrauterine systems as a treatment using in premenopausal women with symptomatic …

[PDF][PDF] Levonorgestrel-releasing intrauterine device use as an alternative to surgical therapy for uterine leiomyoma

T Senol, I Kahramanoglu… - Clin Exp …, 2015 - venus-pro-bucket.s3.amazonaws …
Objective: To evaluate the efficacy of the levonorgestrel-releasing intrauterine system (LNG-
IUS) in the treatment of leiomyoma related menorrhagia and to assess the effect of LNG-IUS …

[HTML][HTML] Levonorgestrel-releasing intrauterine device insertion ameliorates leiomyoma-dependent menorrhagia among women of reproductive age without a …

MM Naki, C Tekcan, N Ozcan, M Cebi - Fertility and sterility, 2010 - Elsevier
Levonorgestrel-(LNG) releasing intrauterine device (IUD) insertion revealed significant
reduction in visual bleeding scores and spotting with an increase in amenorrhea and uterine …

Contraception for midlife women: a review

TA Miller, RH Allen, AM Kaunitz, CA Cwiak - Menopause, 2018 - journals.lww.com
Family planning represents a key component of reproductive health care. Accordingly, the
provision of contraception must span the reproductive age spectrum, including …

Prolactin is expressed in uterine leiomyomas and promotes signaling and fibrosis in myometrial cells

A DiMauro, C Seger, B Minor, AM Amitrano… - Reproductive …, 2022 - Springer
Uterine leiomyomas are benign, estrogen-sensitive, fibrotic smooth muscle cell tumors
occurring in the uterine myometrium. Leiomyomas are a considerable health burden, with a …

Intrauterine progestins, progesterone antagonists, and receptor modulators: a review of gynecologic applications

MI Rodriguez, M Warden, PD Darney - American journal of obstetrics and …, 2010 - Elsevier
Intrauterine progestins, progesterone receptor modulators, and antagonists have many
important current and potential gynecologic applications. This article will describe the …