Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …
Vasopressin and oxytocin receptor systems in the brain: sex differences and sex-specific regulation of social behavior
KM Dumais, AH Veenema - Frontiers in neuroendocrinology, 2016 - Elsevier
The neuropeptides vasopressin (VP) and oxytocin (OT) and their receptors in the brain are
involved in the regulation of various social behaviors and have emerged as drug targets for …
involved in the regulation of various social behaviors and have emerged as drug targets for …
Considering sex as a biological variable in basic and clinical studies: an endocrine society scientific statement
Abstract In May 2014, the National Institutes of Health (NIH) stated its intent to “require
applicants to consider sex as a biological variable (SABV) in the design and analysis of NIH …
applicants to consider sex as a biological variable (SABV) in the design and analysis of NIH …
Measuring oxytocin and vasopressin: bioassays, immunoassays and random numbers
G Leng, N Sabatier - Journal of neuroendocrinology, 2016 - Wiley Online Library
In this review, we consider the ways in which vasopressin and oxytocin have been
measured since their first discovery. Two different ways of measuring oxytocin in widespread …
measured since their first discovery. Two different ways of measuring oxytocin in widespread …
[HTML][HTML] Fatty acid oxidation is impaired in an orthologous mouse model of autosomal dominant polycystic kidney disease
LF Menezes, CC Lin, F Zhou, GG Germino - EBioMedicine, 2016 - thelancet.com
Background The major gene mutated in autosomal dominant polycystic kidney disease was
first identified over 20years ago, yet its function remains poorly understood. We have used a …
first identified over 20years ago, yet its function remains poorly understood. We have used a …
[HTML][HTML] GPCRs: The most promiscuous druggable receptor of the mankind
K Alhosaini, A Azhar, A Alonazi… - Saudi Pharmaceutical …, 2021 - Elsevier
All physiological events in living organisms originated as specific chemical/biochemical
signals on the cell surface and transmitted into the cytoplasm. This signal is translated within …
signals on the cell surface and transmitted into the cytoplasm. This signal is translated within …
[HTML][HTML] Signal transduction in primary cilia–analyzing and manipulating GPCR and second messenger signaling
The primary cilium projects from the surface of most vertebrate cells, where it senses
extracellular signals to regulate diverse cellular processes during tissue development and …
extracellular signals to regulate diverse cellular processes during tissue development and …
[HTML][HTML] Diabetes insipidus: The other diabetes
S Kalra, AH Zargar, SM Jain, B Sethi… - Indian journal of …, 2016 - journals.lww.com
Diabetes insipidus (DI) is a hereditary or acquired condition which disrupts normal life of
persons with the condition; disruption is due to increased thirst and passing of large volumes …
persons with the condition; disruption is due to increased thirst and passing of large volumes …
[HTML][HTML] Sex differences in the brain: a whole body perspective
GJ de Vries, NG Forger - Biology of sex differences, 2015 - Springer
Most writing on sexual differentiation of the mammalian brain (including our own) considers
just two organs: the gonads and the brain. This perspective, which leaves out all other body …
just two organs: the gonads and the brain. This perspective, which leaves out all other body …
Urine osmolality, response to tolvaptan, and outcome in autosomal dominant polycystic kidney disease: results from the TEMPO 3: 4 trial
O Devuyst, AB Chapman, RT Gansevoort… - Journal of the …, 2017 - journals.lww.com
The vasopressin–cAMP–osmolality axis is abnormal in autosomal dominant polycystic
kidney disease (ADPKD). In the Tolvaptan Efficacy and Safety in Management of Autosomal …
kidney disease (ADPKD). In the Tolvaptan Efficacy and Safety in Management of Autosomal …