Emerging role of mitophagy in cardiovascular physiology and pathology
PE Morales, C Arias-Durán, Y Ávalos-Guajardo… - Molecular aspects of …, 2020 - Elsevier
Healthy mitochondrial function is imperative for most tissues, but especially those with a high
energy demand. Robust evidence linking mitochondrial dysfunction with cardiovascular …
energy demand. Robust evidence linking mitochondrial dysfunction with cardiovascular …
Mitochondria-associated endoplasmic reticulum membranes in cardiovascular diseases
P Gao, Z Yan, Z Zhu - Frontiers in cell and developmental biology, 2020 - frontiersin.org
The endoplasmic reticulum (ER) and mitochondria are physically connected to form
dedicated structural domains known as mitochondria-associated ER membranes (MAMs) …
dedicated structural domains known as mitochondria-associated ER membranes (MAMs) …
Increased Drp1 acetylation by lipid overload induces cardiomyocyte death and heart dysfunction
Q Hu, H Zhang, N Gutiérrez Cortés, D Wu… - Circulation …, 2020 - Am Heart Assoc
Rationale: Lipid overload-induced heart dysfunction is characterized by cardiomyocyte
death, myocardial remodeling, and compromised contractility, but the impact of excessive …
death, myocardial remodeling, and compromised contractility, but the impact of excessive …
Adipocyte extracellular vesicles carry enzymes and fatty acids that stimulate mitochondrial metabolism and remodeling in tumor cells
E Clement, I Lazar, C Attané, L Carrié… - The EMBO …, 2020 - embopress.org
Extracellular vesicles are emerging key actors in adipocyte communication. Notably, small
extracellular vesicles shed by adipocytes stimulate fatty acid oxidation and migration in …
extracellular vesicles shed by adipocytes stimulate fatty acid oxidation and migration in …
[HTML][HTML] Differential effects of oleic and palmitic acids on lipid droplet-mitochondria interaction in the hepatic cell line HepG2
A Eynaudi, F Díaz-Castro, JC Bórquez… - Frontiers in …, 2021 - frontiersin.org
Fatty acid overload, either of the saturated palmitic acid (PA) or the unsaturated oleic acid
(OA), causes triglyceride accumulation into specialized organelles termed lipid droplets …
(OA), causes triglyceride accumulation into specialized organelles termed lipid droplets …
[HTML][HTML] Sarcoplasmic reticulum–mitochondria communication in cardiovascular pathophysiology
C Lopez-Crisosto, C Pennanen… - Nature Reviews …, 2017 - nature.com
Repetitive, calcium-mediated contractile activity renders cardiomyocytes critically dependent
on a sustained energy supply and adequate calcium buffering, both of which are provided …
on a sustained energy supply and adequate calcium buffering, both of which are provided …
Metabolic regulation to treat bipolar depression: mechanisms and targeting by trimetazidine
S Khanra, P Reddy, A Giménez-Palomo… - Molecular …, 2023 - nature.com
Bipolar disorder's core feature is the pathological disturbances in mood, often accompanied
by disrupted thinking and behavior. Its complex and heterogeneous etiology implies that a …
by disrupted thinking and behavior. Its complex and heterogeneous etiology implies that a …
Mitochondrial-shaping proteins in cardiac health and disease–the long and the short of it!
SB Ong, SB Kalkhoran, S Hernández-Reséndiz… - … drugs and therapy, 2017 - Springer
Mitochondrial health is critically dependent on the ability of mitochondria to undergo
changes in mitochondrial morphology, a process which is regulated by mitochondrial …
changes in mitochondrial morphology, a process which is regulated by mitochondrial …
[HTML][HTML] Role of mitochondrial lipids in guiding fission and fusion
MA Frohman - Journal of molecular medicine, 2015 - Springer
Clinically important links have been established between mitochondrial function and cardiac
physiology and disease in the context of signaling mechanisms, energy production, and …
physiology and disease in the context of signaling mechanisms, energy production, and …
[HTML][HTML] Mitochondrial network remodeling: an important feature of myogenesis and skeletal muscle regeneration
FA Rahman, J Quadrilatero - Cellular and Molecular Life Sciences, 2021 - Springer
The remodeling of the mitochondrial network is a critical process in maintaining cellular
homeostasis and is intimately related to mitochondrial function. The interplay between the …
homeostasis and is intimately related to mitochondrial function. The interplay between the …