Early-life inflammation promotes depressive symptoms in adolescence via microglial engulfment of dendritic spines
P Cao, C Chen, A Liu, Q Shan, X Zhu, C Jia, X Peng… - Neuron, 2021 - cell.com
Early-life inflammation increases the risk for depression in later life. Here, we demonstrate
how early-life inflammation causes adolescent depressive-like symptoms: by altering the …
how early-life inflammation causes adolescent depressive-like symptoms: by altering the …
Pathophysiology linking depression and type 2 diabetes: psychotherapy, physical exercise, and fecal microbiome transplantation as damage control
Diabetes increases the likelihood of developing depression and vice versa. Research on
this bidirectional association has somewhat managed to delineate the interplay among …
this bidirectional association has somewhat managed to delineate the interplay among …
Prophylactic Effects of Bifidobacterium adolescentis on Anxiety and Depression-Like Phenotypes After Chronic Stress: A Role of the Gut Microbiota-Inflammation Axis
Y Guo, JP Xie, K Deng, X Li, Y Yuan, Q Xuan… - Frontiers in Behavioral …, 2019 - frontiersin.org
Stress disturbs the balance of the gut microbiota and stimulates inflammation-to-brain
mechanisms. Moreover, stress leads to anxiety and depressive disorders. Bifidobacterium …
mechanisms. Moreover, stress leads to anxiety and depressive disorders. Bifidobacterium …
Once induced, it lasts for a long time: the structural and molecular signatures associated with depressive-like behavior after neonatal immune activation
JN Khantakova, NP Bondar, EV Antontseva… - Frontiers in Cellular …, 2022 - frontiersin.org
Adverse factors such as stress or inflammation in the neonatal period can affect the
development of certain brain structures and have negative delayed effects throughout the …
development of certain brain structures and have negative delayed effects throughout the …
Ginsenoside‐Rg1 rescues stress‐induced depression‐like behaviors via suppression of oxidative stress and neural inflammation in rats
Y Li, L Wang, P Wang, C Fan, P Zhang… - Oxidative medicine …, 2020 - Wiley Online Library
Depression is an inflammatory‐related condition, with the progression in neuronal damage
resulting in major depression disorder. Ginsenoside‐Rg1, a sterol extract from the herb …
resulting in major depression disorder. Ginsenoside‐Rg1, a sterol extract from the herb …
[HTML][HTML] Gypenosides reverses depressive behavior via inhibiting hippocampal neuroinflammation
SQ Dong, QP Zhang, JX Zhu, M Chen, CF Li… - Biomedicine & …, 2018 - Elsevier
Gypenosides, a saponins extract isolated from the Gynostemma pentaphyllum plant,
produces neuroprotective effects in the brain. Our previous studies have shown that …
produces neuroprotective effects in the brain. Our previous studies have shown that …
Activation of Nrf2 signaling by salvianolic acid C attenuates NF‑κB mediated inflammatory response both in vivo and in vitro
J Song, W Zhang, J Wang, H Yang, X Zhao… - International …, 2018 - Elsevier
Neurodegenerative diseases are closely related to neuroinflammation. Drugs targeting
inflammation have been proved to be effective in many animal models. Salvianolic acid C …
inflammation have been proved to be effective in many animal models. Salvianolic acid C …
Prior maternal separation stress alters the dendritic complexity of new hippocampal neurons and neuroinflammation in response to an inflammatory stressor in …
Stress during critical periods of neurodevelopment is associated with an increased risk of
developing stress-related psychiatric disorders, which are more common in women than …
developing stress-related psychiatric disorders, which are more common in women than …
Protective effects of tauroursodeoxycholic acid on lipopolysaccharide-induced cognitive impairment and neurotoxicity in mice
Accumulating evidence has shown that tauroursodeoxycholic acid (TUDCA) is
neuroprotective in different animal models of neurological diseases. However, whether …
neuroprotective in different animal models of neurological diseases. However, whether …
GR/NF-κB signaling pathway regulates hippocampal inflammatory responses in diabetic rats with chronic unpredictable mild stress
ZR Li, YS Han, Z Liu, HQ Zhao, J Liu, H Yang… - European journal of …, 2021 - Elsevier
Clinical studies have shown that diabetes can present with underlying depression, and a
combination of the two can lead to emotional, memory and cognitive disorders, closely …
combination of the two can lead to emotional, memory and cognitive disorders, closely …