Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity

R Lang, AL Gundlach, FE Holmes, SA Hobson… - Pharmacological …, 2015 - ASPET
Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

Functions of galanin, spexin and kisspeptin in metabolism, mood and behaviour

EG Mills, C Izzi-Engbeaya, A Abbara… - Nature Reviews …, 2021 - nature.com
The bioactive peptides galanin, spexin and kisspeptin have a common ancestral origin and
their pathophysiological roles are increasingly the subject of investigation. Evidence …

The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease

R Lang, AL Gundlach, B Kofler - Pharmacology & therapeutics, 2007 - Elsevier
The galanin peptide family consists of the “parental” galanin, galanin-message-associated
peptide (GMAP) which derives from the same peptide precursor gene product as galanin …

[图书][B] Fat detection: taste, texture, and post ingestive effects

JP Montmayeur, J Le Coutre - 2009 - taylorfrancis.com
Presents the State-of-the-Art in Fat Taste TransductionA bite of cheese, a few potato chips, a
delectable piece of bacon-a small taste of high-fat foods often draws you back for more. But …

Diet-induced obesity leads to alterations in behavior and gut microbiota composition in mice

REM Júnior, LM de Carvalho, DC Dos Reis… - The Journal of …, 2021 - Elsevier
The high prevalence of obesity and associated metabolic disorders are one of the major
public health problems worldwide. Among the main causal factors of obesity, excessive …

The lateral hypothalamus: an uncharted territory for processing peripheral neurogenic inflammation

M Fakhoury, I Salman, W Najjar, G Merhej… - Frontiers in …, 2020 - frontiersin.org
The roles of the hypothalamus and particularly the lateral hypothalamus (LH) in the
regulation of inflammation and pain have been widely studied. The LH consists of a …

[HTML][HTML] Leptin modulates nutrient reward via inhibitory galanin action on orexin neurons

A Laque, S Yu, E Qualls-Creekmore, S Gettys… - Molecular …, 2015 - Elsevier
Objective Leptin modulates food reward via central leptin receptor (LepRb) expressing
neurons. Food reward requires stimulation of midbrain dopamine neurons and is modulated …

Galanin peptide family regulation of glucose metabolism

P Fang, M Yu, M Shi, P Bo, Z Zhang - Frontiers in Neuroendocrinology, 2020 - Elsevier
Recent preclinical and clinical studies have indicated that the galanin peptide family may
regulate glucose metabolism and alleviate insulin resistance, which diminishes the …

Galanin and its receptors: a novel strategy for appetite control and obesity therapy

P Fang, M Yu, L Guo, P Bo, Z Zhang, M Shi - Peptides, 2012 - Elsevier
The rapid increase in the prevalence of overweight and obesity is becoming an important
health problem. Overweight and obesity may cause several metabolic complications …

[HTML][HTML] Galanin enhances systemic glucose metabolism through enteric Nitric Oxide Synthase-expressed neurons

A Abot, A Lucas, T Bautzova, A Bessac, A Fournel… - Molecular …, 2018 - Elsevier
Objective Decreasing duodenal contraction is now considered as a major focus for the
treatment of type 2 diabetes. Therefore, identifying bioactive molecules able to target the …