Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)

X Xu, KL Poulsen, L Wu, S Liu, T Miyata… - Signal transduction and …, 2022 - nature.com
Non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) has become the leading
cause of liver disease worldwide. NASH, an advanced form of NAFL, can be progressive …

[HTML][HTML] A new perspective on NAFLD: Focusing on the crosstalk between peroxisome proliferator-activated receptor alpha (PPARα) and farnesoid X receptor (FXR)

S Zhou, H You, S Qiu, D Yu, Y Bai, J He, H Cao… - Biomedicine & …, 2022 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is primarily caused by abnormal lipid metabolism
and the accumulation of triglycerides in the liver. NAFLD is also associated with hepatic …

An updated meta-analysis of effects of curcumin on metabolic dysfunction-associated fatty liver disease based on available evidence from Iran and Thailand

T Lukkunaprasit, A Tansawet, S Boonmanunt… - Scientific Reports, 2023 - nature.com
Metabolic dysfunction-associated fatty liver disease (MAFLD) is a common cause of chronic
liver disease and can progress to nonalcoholic steatohepatitis and cirrhosis. This study aims …

Fibrogenic pathways in metabolic dysfunction associated fatty liver disease (MAFLD)

P Subramanian, J Hampe, F Tacke… - International Journal of …, 2022 - mdpi.com
The prevalence of nonalcoholic fatty liver disease (NAFLD), recently also re-defined as
metabolic dysfunction associated fatty liver disease (MAFLD), is rapidly increasing …

Lessons on drug development: a literature review of challenges faced in nonalcoholic fatty liver disease (NAFLD) clinical trials

JYS Chen, D Chua, CO Lim, WX Ho… - International Journal of …, 2022 - mdpi.com
NAFLD is the most common chronic liver disease worldwide, occurring in both obese and
lean patients. It can lead to life-threatening liver diseases and nonhepatic complications …

360-degree perspectives on obesity

M Cuciureanu, CC Caratașu, L Gabrielian… - Medicina, 2023 - mdpi.com
Alarming statistics show that the number of people affected by excessive weight has
surpassed 2 billion, representing approximately 30% of the world's population. The aim of …

Mediterranean diet improves plasma biomarkers related to oxidative stress and inflammatory process in patients with non-alcoholic fatty liver disease

MM Quetglas-Llabrés, M Monserrat-Mesquida… - Antioxidants, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) shows liver fat depots without alcohol
consumption. NAFLD does not have specific drug therapies, with a healthy lifestyle and …

Helminth infection and helminth-derived products: A novel therapeutic option for non-alcoholic fatty liver disease

X Liu, Y Jiang, J Ye, X Wang - Frontiers in immunology, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is closely related to obesity, diabetes, and
metabolic syndrome (MetS), and it has become the most common chronic liver disease …

[HTML][HTML] Protective effect of traditional Chinese medicine on non-alcoholic fatty liver disease and liver cancer by targeting ferroptosis

Q Wu, Z Chen, Y Ding, Y Tang, Y Cheng - Frontiers in Nutrition, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease with high incidence and
is closely related to metabolic syndrome. If not controlled, it may eventually become …

Clinical Classification of Obesity and Implications for Metabolic Dysfunction-Associated Fatty Liver Disease and Treatment

Y Ding, Q Deng, M Yang, H Niu, Z Wang… - … Syndrome and Obesity, 2023 - Taylor & Francis
Obesity, and metabolic dysfunction-associated fatty liver disease (MAFLD) have reached
epidemic proportions globally. Obesity and MAFLD frequently coexist and act synergistically …