Heart failure with reduced ejection fraction (HFrEF) develops when cardiac output falls as a
result of cardiac injury. The most well-recognized of the compensatory homeostatic …

Short sleep duration has a substantial influence on the overall health of an individual. Short
sleep time can be a consequence of lifestyle habits, environmental factors, or the presence …

Complex and bidirectional interactions between the renin–angiotensin system (RAS) and
autonomic nervous system have been well established for cardiovascular regulation under …

Background: The relationship between mortality and heart rate remains unclear for patients
with heart failure with reduced ejection fraction in either sinus rhythm or atrial fibrillation (AF) …

Heart failure (HF) is a complex clinical syndrome characterized by the activation of at least
several neurohumoral pathways that have a common role in maintaining cardiac output and …

Synchronization of molecular, metabolic, and cardiovascular circadian oscillations is
fundamental to human health. Sleep-disordered breathing, which disrupts such temporal …

Patients with cardiovascular disease show autonomic dysfunction, including sympathetic
activation and vagal withdrawal, which leads to fatal events. This review aims to place …

Atrial fibrillation is the most common sustained arrhythmia and is associated with significant
morbidity and mortality. The autonomic nervous system has a significant role in the milieu …

Vagus nerve stimulation (VNS) is an effective technique for the treatment of refractory
epilepsy and shows potential for the treatment of a range of other serious conditions …

Background Central sleep apnoea is a serious breathing disorder associated with poor
outcomes. The remedé system (Respicardia Inc, Minnetonka, MN, USA) is an implantable …