Advances of zebrafish in neurodegenerative disease: from models to drug discovery
X Wang, JB Zhang, KJ He, F Wang… - Frontiers in Pharmacology, 2021 - frontiersin.org
Neurodegenerative disease (NDD), including Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis, are characterized by the progressive loss of neurons which …
amyotrophic lateral sclerosis, are characterized by the progressive loss of neurons which …
The comparative neuroanatomy and neurochemistry of zebrafish CNS systems of relevance to human neuropsychiatric diseases
P Panula, YC Chen, M Priyadarshini, H Kudo… - Neurobiology of …, 2010 - Elsevier
Modulatory neurotransmitters which signal through G protein-coupled receptors control
brain functions which deteriorate in degenerative brain diseases. During the past decade …
brain functions which deteriorate in degenerative brain diseases. During the past decade …
Zebrafish as a model organism for neurodegenerative disease
K Chia, A Klingseisen, D Sieger… - Frontiers in molecular …, 2022 - frontiersin.org
The zebrafish is increasingly recognized as a model organism for translational research into
human neuropathology. The zebrafish brain exhibits fundamental resemblance with human …
human neuropathology. The zebrafish brain exhibits fundamental resemblance with human …
Zebrafish models of human disease: gaining insight into human disease at ZFIN
YM Bradford, S Toro, S Ramachandran, L Ruzicka… - ILAR …, 2017 - academic.oup.com
Abstract The Zebrafish Model Organism Database (ZFIN; https://zfin. org) is the central
resource for genetic, genomic, and phenotypic data for zebrafish (Danio rerio) research …
resource for genetic, genomic, and phenotypic data for zebrafish (Danio rerio) research …
Zebrafish as an animal model for drug discovery in Parkinson's disease and other movement disorders: a systematic review
RL Vaz, TF Outeiro, JJ Ferreira - Frontiers in neurology, 2018 - frontiersin.org
Movement disorders can be primarily divided into hypokinetic and hyperkinetic. Most of the
hypokinetic syndromes are associated with the neurodegenerative disorder Parkinson's …
hypokinetic syndromes are associated with the neurodegenerative disorder Parkinson's …
Zebrafish embryos as models for embryotoxic and teratological effects of chemicals
The experimental virtues of the zebrafish embryo such as small size, development outside of
the mother, cheap maintenance of the adult made the zebrafish an excellent model for …
the mother, cheap maintenance of the adult made the zebrafish an excellent model for …
Zebrafish assays for drug toxicity screening
AL Rubinstein - Expert opinion on drug metabolism & toxicology, 2006 - Taylor & Francis
Zebrafish are vertebrate organisms that are of growing interest for preclinical drug discovery
applications. Zebrafish embryos develop most of the major organ systems present in …
applications. Zebrafish embryos develop most of the major organ systems present in …
Zebrafish and medaka: important animal models for human neurodegenerative diseases
J Wang, H Cao - International journal of molecular sciences, 2021 - mdpi.com
Animal models of human neurodegenerative disease have been investigated for several
decades. In recent years, zebrafish (Danio rerio) and medaka (Oryzias latipes) have become …
decades. In recent years, zebrafish (Danio rerio) and medaka (Oryzias latipes) have become …
Modulatory neurotransmitter systems and behavior: towards zebrafish models of neurodegenerative diseases
P Panula, V Sallinen, M Sundvik, J Kolehmainen… - Zebrafish, 2006 - liebertpub.com
The modulatory aminergic neurotransmitters are involved in practically all important
physiological systems in the brain, and many of them are also involved in human central …
physiological systems in the brain, and many of them are also involved in human central …
Modeling neurodegeneration in zebrafish
Y Xi, S Noble, M Ekker - Current neurology and neuroscience reports, 2011 - Springer
The zebrafish, Danio rerio, has been established as an excellent vertebrate model for the
study of developmental biology and gene function. It also has proven to be a valuable model …
study of developmental biology and gene function. It also has proven to be a valuable model …