Natural products are mainly secondary metabolites produced by plants, microorganisms,
and animals, which are still abundant in modern drug discovery. Terpenoids are the most …

The pool of abundant chiral terpene building blocks (ie,“chiral pool terpenes”) has long
served as a starting point for the chemical synthesis of complex natural products, including …

Daphnenoids A–C (1–3), three unusual sesquiterpenes with distinctive ring skeletons,
together with a biogenetically related daphnenoid D (4) were obtained from the herb of …

Crop domestication usually leads to the narrowing genetic diversity. However, human
selection mainly focuses on visible traits, such as yield and plant morphology, with most …

Cycloaddition reactions are among the most widely used reactions in chemical synthesis.
Nature achieves these cyclization reactions with a variety of enzymes, including Diels …

Fungi are widely distributed in the terrestrial environment, freshwater, and marine habitat.
Only approximately 100,000 of these have been classified although there are about 5.1 …

The structure elucidation, biosynthesis, and biological activity of marine carbotricyclic
sesquiterpene compounds are reviewed from the pioneering results to the end of 2015 …

Terpene cyclases catalyze one of the most powerful transformations with respect to
efficiency and selectivity in natural product (bio) synthesis. In such polyene cyclizations …

This review summarizes new findings concerning the sources and characteristics of various
natural products that can be extracted from mangrove-associated microbes over the past …

Metabolic engineering of Saccharomyces cerevisiae focusing on the cytoplasm for
sustainable terpenoid production is commonly practiced. However, engineering organelles …