Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy
H Li, Y Kim, H Jung, JY Hyun, I Shin - Chemical Society Reviews, 2022 - pubs.rsc.org
Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …
Trends in peptide drug discovery
Since the introduction of insulin almost a century ago, more than 80 peptide drugs have
reached the market for a wide range of diseases, including diabetes, cancer, osteoporosis …
reached the market for a wide range of diseases, including diabetes, cancer, osteoporosis …
Theranostic Nuclear Medicine with Gallium-68, Lutetium-177, Copper-64/67, Actinium-225, and Lead-212/203 Radionuclides: Focus Review
Molecular changes in malignant tissue can lead to an increase in the expression levels of
various proteins or receptors that can be used to target the disease. In oncology, diagnostic …
various proteins or receptors that can be used to target the disease. In oncology, diagnostic …
Nanomaterials for theranostics: recent advances and future challenges
In 2004, the US Food and Drug Administration (FDA) released an important report entitled
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …
Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery
Design and functionalization strategies for multifunctional nanocarriers (eg, nanoparticles,
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …
A molecular imaging primer: modalities, imaging agents, and applications
ML James, SS Gambhir - Physiological reviews, 2012 - journals.physiology.org
Molecular imaging is revolutionizing the way we study the inner workings of the human
body, diagnose diseases, approach drug design, and assess therapies. The field as a whole …
body, diagnose diseases, approach drug design, and assess therapies. The field as a whole …
Theranostics: combining imaging and therapy
SS Kelkar, TM Reineke - Bioconjugate chemistry, 2011 - ACS Publications
Employing theranostic nanoparticles, which combine both therapeutic and diagnostic
capabilities in one dose, has promise to propel the biomedical field toward personalized …
capabilities in one dose, has promise to propel the biomedical field toward personalized …
Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease
TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …
processes at the molecular and cellular levels in humans and other living systems …
Somatostatin receptors: from signaling to clinical practice
M Theodoropoulou, GK Stalla - Frontiers in neuroendocrinology, 2013 - Elsevier
Somatostatin is a peptide with a potent and broad antisecretory action, which makes it an
invaluable drug target for the pharmacological management of pituitary adenomas and …
invaluable drug target for the pharmacological management of pituitary adenomas and …
Peptide-based imaging agents for cancer detection
Selective receptor-targeting peptide based agents have attracted considerable attention in
molecular imaging of tumor cells that overexpress corresponding peptide receptors due to …
molecular imaging of tumor cells that overexpress corresponding peptide receptors due to …