Nitric oxide (NO) has long been known as endothelium-derived relaxing factor. It is a
vasodilator, modulating vascular tone, blood pressure and hemodynamics, a role exploited …

Survival of multicellular organisms depends on their ability to fight infection, metabolize
nutrients, and store energy for times of need. Unsurprisingly, therefore, immunoregulatory …

Periodontal disease is a chronic inflammatory disorder of the tissues surrounding the teeth,
with evidence of systemic effects. Some studies showed the benefit of periodontal therapy …

In recent decades, the most successful strategy for controlling blood pressure has been
inhibition of the angiotensin-converting enzyme (ACE). ACE inhibitors of chemical synthesis …

Hypertension is a multifactorial disease that affects approximately one billion subjects
worldwide and is a major risk factor associated with cardiovascular events, including …

Antihypertensive agents may, even within the same class, exert variable effects on arterial
stiffness variables. Nebivolol could have a better impact than atenolol on arterial stiffness, by …

Nitric oxide (NO) is a vasoactive substance synthesized from l-arginine by neuronal (NOS1),
endothelial (NOS3), and inducible (NOS2) nitric oxide synthases. NOS3 is the most …

Patients with decompensated cirrhosis are at risk of developing acute kidney injury (AKI).
Studies have suggested that inhibition of the Renin-Angiotensin System (RAS) has certain …

J Clin Hypertens (Greenwich). The goals of antihypertensive therapy include optimal
reduction in blood pressure (BP) while providing a favorable tolerability profile that promotes …

Arterial stiffness is an independent predictor of cardiovascular (CV) morbidity and mortality
in patients with hypertension, as well as a potential therapeutic target. There is increasing …