Novel chalcone-like compounds, LQFM332 (4), LQFM333 (5), and LQFM341 (6), were
synthesized and their activity against Leishmania (L.) amazonensis was evaluated and …

Seaweeds present a wide variety of interesting bioactive molecules. In the present work we
evaluated the biological activity of the dichloromethane/methanol (2: 1) extract (DME) from …

This study aimed to verify the effect of the treatment with A. satureioides essential oil (free
and nanoencapsulated forms) and diminazene aceturate on hematological and biochemical …

Electron paramagnetic resonance (EPR) spectroscopy of spin labels was used to study the
interactions of amphotericin B (AmB) with the plasma membrane of Leishmania …

hydroxy-2-nonenal (HNE) is a reactive aldehyde produced by cells under conditions of
oxidative stress, which has been shown to react with proteins and …

This work evaluated the in vitro and in vivo activity of TDZ 2 on Trypanosoma cruzi
amastigotes and determined the possible mechanism of action of this compound on T. cruzi …

Leishmaniasis is a neglected infection that is caused by Leishmania protozoa, affecting
millions of people worldwide, mainly in tropical and subtropical regions. This disease has …

A series of novel 1-(substituted-phenyl)-3-(4, 5-dihydro-1, 3-oxazol-2-yl)-9 H-β-carboline (8a-
8i) and 1-(substituted-phenyl)-3-(5, 6-dihydro-4 H-1, 3-oxazin-2-yl)-9 H-β-carboline (9a-9h) …

Human trypanosomiasis is a parasitic disease among poor people in Africa and Latin
America. Therapy against African and American trypanosomiasis is based on a few drugs …

Chagas' disease is an infection that is caused by the protozoan Trypanosoma cruzi, affecting
millions of people worldwide. Because of severe side effects and variable efficacy, the …