On-chip recapitulation of the tumor microenvironment: A decade of progress
SM Giannitelli, V Peluzzi, S Raniolo, G Roscilli… - Biomaterials, 2024 - Elsevier
One of the hurdles to the development of new anticancer therapies is the lack of in vitro
models which faithfully reproduce the in vivo tumor microenvironment (TME). Understanding …
models which faithfully reproduce the in vivo tumor microenvironment (TME). Understanding …
Integrating microfluidics and synthetic biology: advancements and diverse applications across organisms
C Leal-Alves, Z Deng, N Kermeci, SCC Shih - Lab on a Chip, 2024 - pubs.rsc.org
Synthetic biology is the design and modification of biological systems for specific functions,
integrating several disciplines like engineering, genetics, and computer science. The field of …
integrating several disciplines like engineering, genetics, and computer science. The field of …
Advanced sequencing-based high-throughput and long-read single-cell transcriptome analysis
Cells are the fundamental building blocks of living systems, exhibiting significant
heterogeneity. The transcriptome connects the cellular genotype and phenotype, and …
heterogeneity. The transcriptome connects the cellular genotype and phenotype, and …
Gravity‐Oriented Microfluidic Device for Biocompatible End‐to‐End Fabrication of Cell‐Laden Microgels
S Chen, Z Wu, Q Zhang, Y Li, H Yao, S Chen, T Xie… - Small, 2024 - Wiley Online Library
Droplet microfluidics are extensively utilized to generate monodisperse cell‐laden microgels
in biomedical applications. However, maintaining cell viability is still challenging due to …
in biomedical applications. However, maintaining cell viability is still challenging due to …
Understanding Macrophage‐Tumor Interactions: Insights from Single‐Cell Behavior Monitoring in a Sessile Microdroplet System
J Lin, Q Zhang, T Xie, Z Wu, Y Hou, Y Song… - Small …, 2024 - Wiley Online Library
Interaction between tumor‐associated macrophages and tumor cells is crucial for tumor
development, metastasis, and the related immune process. However, the macrophages are …
development, metastasis, and the related immune process. However, the macrophages are …
[HTML][HTML] In situ investigation of detoxification and metabolic effects of polyfluoroalkyl substances on metal–organic frameworks combined with cell-cultured …
N Xu, H Lin, Q Du, S Dong, J Cheng, P Wang, JM Lin - Lab on a Chip, 2023 - pubs.rsc.org
Over 9000 types of per-and polyfluoroalkyl substances (PFASs) have been produced that
exhibit environmental persistence, bioaccumulation and biotoxicity, and pose a potential …
exhibit environmental persistence, bioaccumulation and biotoxicity, and pose a potential …
[HTML][HTML] Rapid Microfluidic Immuno-Biosensor Detection System for the Point-of-Care Determination of High-Sensitivity Urinary C-Reactive Protein
A microfluidic immuno-biosensor detection system consisting of a microfluidic spectrum chip
and a micro-spectrometer detection device is presented for the rapid point-of-care (POC) …
and a micro-spectrometer detection device is presented for the rapid point-of-care (POC) …
Microfluidic-based platforms for cell-to-cell communication studies
Intercellular communication is critical to the understanding of human health and disease
progression. However, compared to traditional methods with inefficient analysis, microfluidic …
progression. However, compared to traditional methods with inefficient analysis, microfluidic …