The newer progestogens desogestrel, norgestimate, gestodene, dienogest and nomegestrol
share the common property of having weak or no androgenic effects, but there is great …

There are large inter-and intra-individual variations in the serum concentrations of natural
and synthetic sex steroids irrespective of the route of administration. Oral ingestion of …

Several 5-(4-chlorophenyl)-1, 2-dihydro-5 H-chromeno [3, 4-f] quinolines were prepared to
determine the effects of substitution at C (8) and C (9) on the progestational activity of this …

The adrenal cortex elaborates two major groups of steroids that have been arbitrarily
classified as glucocorticoids and mineralocorticoids, despite the fact that carbohydrate …

There is great concern over the long-term influence of oral contraceptives on the
development of breast cancer in women. Oestrogens are known to stimulate the growth of …

The newer progestogens gestodene, desogestrel and norgestimate were developed in an
attempt to produce agents with more selective progestational activity that would improve …

The development of rational pharmaceutical polymorph control systems from crystallization
requires the experimental manipulation of both thermodynamic and kinetic factors. Herein …

Abstract Dihydrospirorenone (6β, 7β, 15β, 16β-dimethylen-3-oxo-17a-pregn-4-en-21, 17-
carbolacton) is a new type of progestin with no other agonistic activities, in particular no …

Gestodene is a novel progestin used in oral contracepttives with an increased separation of
progestogenic versus androgenic activity and a distinct antimineralocorticoid activity. This …

Progestins used in oral contraceptive formulations available in the United States include
norgestimate, desogestrel, norethindrone, norethindrone acetate, and levonorgestrel …