Natural killer (NK) cells and natural killer T (NKT) cells are subsets of lymphocytes that share
some phenotypical and functional similarities. Both cell types can rapidly respond to the …

Much has been made about JLW Thudichum's colorful, and one could say clairvoyant,
naming of sphingosine “in commemoration of the many enigmas which it presented to the …

Natural killer T (NKT) cells are specialized CD1d-restricted T cells that recognize lipid
antigens. Following stimulation, NKT cells lead to downstream activation of both innate and …

Natural killer T (NKT) cells are innate-like T cells that rapidly produce a variety of cytokines
following T cell receptor (TCR) activation and can shape the immune response in many …

Cells of the innate immune system interact with pathogens via conserved pattern-recognition
receptors, whereas cells of the adaptive immune system recognize pathogens through …

Antibody responses are classified according to whether B cells receive help from T cells—
that is, whether they are thymus-dependent (TD) responses or thymus-independent (TI) …

Invariant natural killer T (iNKT) cells are non-conventional lipid-reactive αβ T lymphocytes
that play a key role in host responses during viral infections, in particular through the swift …

The liver lymphocyte population is enriched with natural killer (NK) cells, which play a key
role in host defense against viral infection and tumor transformation. Recent evidence from …

Mucosal-associated invariant T (MAIT) cells and invariant natural killer T (iNKT) cells are
innate-like T cells that function at the interface between innate and adaptive immunity. They …

Many hematopoietic cell types express CD1d and are capable of presenting glycolipid
antigens to invariant natural killer T cells (iNKT cells). However, the question of which cells …