[HTML][HTML] Cyclotron Production of Gallium-68 Radiopharmaceuticals Using the 68Zn(p,n)68Ga Reaction and Their Regulatory Aspects

Z Ashhar, MF Ahmad Fadzil, MF Othman, NA Yusof… - Pharmaceutics, 2022 - mdpi.com
Designing and implementing various radionuclide production methods guarantees a
sustainable supply, which is important for medical use. The use of medical cyclotrons for …

Advancements in the development of radiopharmaceuticals for nuclear medicine applications in the treatment of bone metastases

MR Dyer, Z Jing, K Duncan, J Godbe… - Nuclear Medicine and …, 2024 - Elsevier
Bone metastases are a painful and complex condition that overwhelmingly impacts the
prognosis and quality of life of cancer patients. Over the years, nuclear medicine has made …

[HTML][HTML] Dissolution of Molybdenum in Hydrogen Peroxide: A Thermodynamic, Kinetic and Microscopic Study of a Green Process for 99mTc Production

F Cicconi, A Ubaldini, A Fiore, A Rizzo, S Cataldo… - Molecules, 2023 - mdpi.com
99mTc-based radiopharmaceuticals are the most commonly used medical radioactive
tracers in nuclear medicine for diagnostic imaging. Due to the expected global shortage of …

Planar deposition of Nb thin films by HiPIMS for superconducting radiofrequency applications

CPA Carlos, S Leith, G Rosaz, S Pfeiffer, C Senatore - Vacuum, 2024 - Elsevier
Cost efficiency and sustainability are critical challenges for future accelerator machines. Nb-
coated Cu (Nb/Cu) superconducting radiofrequency (SRF) accelerating cavities, while …

Digital twins in dosimetry and radiotherapy, a survey and some applications

M Sumini, F Teodori, L Isolan - Radiation Physics and Chemistry, 2024 - Elsevier
Abstract Digital Twins (DTs) are emerging as a powerful tool in several applications,
including Dosimetry and Radiotherapy (RT). Indeed, DTs have increased their effectiveness …

Performance evaluation of Gallium-68 radiopharmaceuticals production using liquid target PETtrace 800 cyclotron

Z Ashhar, MFA Fadzil, ZM Safee, F Aziz… - Applied Radiation and …, 2024 - Elsevier
Due to increased demand, cyclotron has an expanding role in producing Gallium-68 (68 Ga)
radiopharmaceuticals using solid and liquid targets. Though the liquid target produces lower …

Research on the production of 99mTc and 99Mo using multi-layer targets at APEP

Q Dong, H Jing, W Li, Z Tan - Radiation Physics and Chemistry, 2024 - Elsevier
One of the most effective methods for producing radioisotopes aimed at Nuclear Medicine
applications, such as 99m Tc and 99 Mo, is to use a compact proton accelerator located …

[HTML][HTML] Remote Monitoring the Parameters of Interest in the 18O Isotope Separation Technological Process

A Codoban, H Silaghi, S Dale, V Muresan - Processes, 2023 - mdpi.com
This manuscript presents the remote monitoring of the main parameters in the 18O isotope
separation technological process. It proposes to monitor the operation of the five cracking …

Progress of photonuclear cross sections for medical radioisotope production at the SLEGS energy domain

X Pang, BH Sun, LH Zhu, GH Lu, HB Zhou… - Nuclear Science and …, 2023 - Springer
Photonuclear reactions using a laser Compton scattering (LCS) gamma source provide a
new method for producing radioisotopes for medical applications. Compared with the …

The development of cyclotron-based radiopharmaceuticals: a comprehensive review of 64Cu and 123I-radiolabeled urea-based small molecule PSMA ligands

LA Hasnowo, MS Larkina, AA Garapatski… - … of Radioanalytical and …, 2023 - Springer
Abstract 64Cu and 123I are attracting attention in taking up their role in the development and
practical use of PSMA-targeting radiopharmaceuticals. The development of urea-based …