[HTML][HTML] Mechanism of resveratrol-induced programmed cell death and new drug discovery against cancer: a review

JY Jang, E Im, ND Kim - International journal of molecular sciences, 2022 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene), a polyphenol found in grapes, red wine,
peanuts, and apples, has been reported to exhibit a wide range of biological and …

[HTML][HTML] Anti-cancer properties of resveratrol: a focus on its impact on mitochondrial functions

L Kursvietiene, DM Kopustinskiene, I Staneviciene… - Antioxidants, 2023 - mdpi.com
Cancer is one of the most serious public health issues worldwide, demanding ongoing
efforts to find novel therapeutic agents and approaches. Amid growing interest in the …

[HTML][HTML] Celastrol inhibits rheumatoid arthritis by inducing autophagy via inhibition of the PI3K/AKT/mTOR signaling pathway

J Yang, J Liu, J Li, M Jing, L Zhang, M Sun… - International …, 2022 - Elsevier
Objective Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder of the
synovial joints. Celastrol (Cel) is a quinone-methylated triterpenoid extracted from …

[HTML][HTML] Nano-based drug delivery of polyphenolic compounds for cancer treatment: Progress, opportunities, and challenges

W Jia, L Zhou, L Li, P Zhou, Z Shen - Pharmaceuticals, 2023 - mdpi.com
Polyphenols and their derivates, a kind of natural product distributed in herb plants,
vegetables, and fruits, are the most abundant antioxidants in the human diet and have been …

Destruction of the cellular antioxidant pool contributes to resveratrol‐induced senescence and apoptosis in lung cancer

C Liang, K Yi, X Zhou, X Li, C Zhong… - Phytotherapy …, 2023 - Wiley Online Library
Resveratrol (RES) has various pharmacological bioactivities and its anticancer effects in
lung cancer have been proven. However, the underlying mechanisms of action of RES in …

[HTML][HTML] Certain Fermented Foods and their possible Health effects with a focus on Bioactive compounds and microorganisms

G Deveci, E Çelik, D Ağagündüz, E Bartkiene… - Fermentation, 2023 - mdpi.com
Fermented foods refer to beverages or foods made by carefully regulated microbial growth
and the enzymatic conversion of dietary components. Fermented foods have recently …

[HTML][HTML] Targeting inflammation in non-small cell lung cancer through drug repurposing

T Rajasegaran, CW How, A Saud, A Ali, JCW Lim - Pharmaceuticals, 2023 - mdpi.com
Lung cancer is the most common cause of cancer-related deaths. Lung cancers can be
classified as small-cell (SCLC) or non-small cell (NSCLC). About 84% of all lung cancers …

[HTML][HTML] Akt/mTOR targeting activity of resveratrol derivatives in non-small lung cancer

B Innets, S Thongsom, K Petsri, S Racha, M Yokoya… - Molecules, 2022 - mdpi.com
The Akt-mTOR signal is important for the survival and proliferation of cancer cells and has
become an interesting drug target. In this study, five resveratrol derivatives were evaluated …

Therapeutic effects of resveratrol on epigenetic mechanisms in age‐related diseases: A comprehensive review

S Zhang, F Kiarasi - Phytotherapy Research, 2024 - Wiley Online Library
Recently, various studies have shown that epigenetic changes are associated with aging
and age‐related diseases. Both animal and human models have revealed that epigenetic …

Bioresponsive and multifunctional cyclodextrin-based non-viral nanocomplexes in cancer therapy: Building foundations for gene and drug delivery, immunotherapy …

Q Lu - Environmental Research, 2023 - Elsevier
The interest towards application of nanomaterials in field of cancer therapy is that the
drawbacks of conventional therapies including chemoresistance, radio-resistance and lack …