The pediatric common variable immunodeficiency—from genetics to therapy: a review
A Szczawinska-Poplonyk, E Schwartzmann… - European Journal of …, 2022 - Springer
Common variable immunodeficiency (CVID) is the most prevalent antibody deficiency,
characterized by remarkable genetic, immunological, and clinical heterogeneity. The …
characterized by remarkable genetic, immunological, and clinical heterogeneity. The …
Lymphocytes subsets in correlation with clinical profile in CVID patients without monogenic defects
Objectives: Common variable immunodeficiency (CVID) patients experience clinical
manifestations rather than recurrent respiratory infections including autoimmunity …
manifestations rather than recurrent respiratory infections including autoimmunity …
HCoV-and SARS-CoV-2 cross-reactive T cells in CVID patients
S Steiner, F Sotzny, S Bauer, IK Na… - Frontiers in …, 2020 - frontiersin.org
The inability of patients with CVID to mount specific antibody responses to pathogens has
raised concerns on the risk and severity of SARS-CoV-2 infection, but there might be a role …
raised concerns on the risk and severity of SARS-CoV-2 infection, but there might be a role …
Evaluation of clinical and immunological alterations associated with ICF syndrome
Purpose Immunodeficiency with centromeric instability and facial anomalies (ICF) syndrome
is a rare autosomal recessive combined immunodeficiency. The detailed immune responses …
is a rare autosomal recessive combined immunodeficiency. The detailed immune responses …
Immunophenotypic and functional analysis of lymphocyte subsets in common variable immunodeficiency patients without monogenic defects
F Tofighi Zavareh, A Mirshafiey… - Scandinavian …, 2022 - Wiley Online Library
Common variable immunodeficiency (CVID) is accompanied by various lymphocyte
abnormalities believed to be mostly responsible for disease features in patients with no …
abnormalities believed to be mostly responsible for disease features in patients with no …
Clinical and laboratory factors affecting the prognosis of severe combined immunodeficiency
Purpose Severe combined immunodeficiency (SCID) is one of the most severe forms of
inborn errors of immunity characterized by absence or loss of function in T cells. The long …
inborn errors of immunity characterized by absence or loss of function in T cells. The long …
Reference values for T and B lymphocyte subpopulations in Turkish children and adults
Ö Besci, D Başer, İ Öğülür… - Turkish journal of …, 2021 - journals.tubitak.gov.tr
Background/aim: Established reference values are critical for the interpretation of
immunologic assessments. In particular, the proportion and absolute counts of T-and B-cell …
immunologic assessments. In particular, the proportion and absolute counts of T-and B-cell …
Immune dysregulation in pediatric common variable immunodeficiency: implications for the diagnostic approach
A Szczawińska-Popłonyk, K Ta̧polska-Jóźwiak… - Frontiers in …, 2022 - frontiersin.org
Infections and infectious complications are hallmarks of common variable immunodeficiency
(CVID) and the leading cause of morbidity and mortality in affected patients at any age …
(CVID) and the leading cause of morbidity and mortality in affected patients at any age …
Soluble interleukin-2 receptor is a promising serum biomarker for granulomatous disease in common variable immune deficiency
AC van Stigt, VASH Dalm, NMA Nagtzaam… - Journal of Clinical …, 2021 - Springer
To the editor: Common variable immune deficiency (CVID) is a primary antibody deficiency
characterized by a marked decrease of immunoglobulin (Ig) G in combination with low IgA …
characterized by a marked decrease of immunoglobulin (Ig) G in combination with low IgA …
Altered immune response in organic acidemia
I Altun, A Kiykim, T Zubarioglu… - Pediatrics …, 2022 - Wiley Online Library
Background Most patients with organic acidemia suffer from recurrent infections. Although
neutropenia has been reported in multiple studies, other components of the immune system …
neutropenia has been reported in multiple studies, other components of the immune system …