Death is the inevitable fate of all living organisms, whether at the individual or cellular level.
For a long time, cell death was believed to be an undesirable but unavoidable final outcome …

Ferroptosis is a newly discovered type of cell death triggered by intracellular phospholipid
peroxidation that is morphologically, biologically and genetically distinct from other types of …

Deciphering the molecular downstream consequences of severe acute respiratory
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …

Pyroptosis is closely associated with tumors and inflammatory diseases. By enhancing
pyroptosis, direct and immune-response-triggered deaths of tumor cells are increased …

Pyroptosis, one kind of inflammatory regulated cell death, is involved in various inflammatory
diseases, including acute kidney injury (AKI). Besides Gasdermin D (GSDMD), GSDME is a …

As an emerging cancer therapeutic target, non-apoptotic cell death such as ferroptosis,
necroptosis and pyroptosis, etc., has revealed significant potential in cancer treatment for …

Ulcerative colitis (UC) is a chronic relapsing inflammatory disease of the colorectal area that
demonstrates a dramatically increasing incidence worldwide. This study provides novel …

Aim: This study aims to identify pyroptosis-related genes (PRGs), their functional immune
characteristics, and distinct pyroptosis-related clusters in periodontitis. Methods …

Pyroptosis is one special type of lytic programmed cell death, featured in cell swelling,
rupture, secretion of cell contents and remarkable proinflammation effect. In the process of …

Non-apoptotic cell death such as ferroptosis and pyroptosis has shed new light on cancer
treatment, whereas combinational therapy using both these mechanisms has not yet been …