Eukaryotic cells contain various Ca2+-effector proteins that mediate cellular responses to
changes in intracellular Ca2+ levels. A unique class of these proteins—annexins—can bind …

In normal healthy cells phosphatidylserine is located in the inner leaflet of the plasma
membrane. However, on activated platelets, dying cells and under specific circumstances …

Eukaryotic cells possess a universal repair machinery that ensures rapid resealing of
plasma membrane disruptions. Before resealing, the torn membrane is submitted to …

Synucleins are a family of presynaptic membrane binding proteins. α-Synuclein, the
principal member of this family, is mutated in familial Parkinson disease. To gain insight into …

In this review the roles of specific proteins during the first step of mineralization and
nucleation are discussed. Mineralization is initiated inside the extracellular organelles …

Introduction 3. Morphology of matrix vesicles (MVs) 3.1. Conventional transmission electron
microscopy 3.2. Cryofixation, freeze-substitution electron microscopy 3.3. Freeze-fracture …

Introduction: Recent advances in pharmacological therapies to treat ocular diseases such as
glaucoma, age-related macular degeneration, diabetic macular edema and retinal vascular …

Annexins are a family of proteins characterized by their ability to bind anionic membranes in
response to Ca2+-activation. They are involved in a multitude of cellular functions including …

The vertebrate annexin superfamily (AnxA) consists of 12 members of a calcium (Ca2+) and
phospholipid binding protein family which share a high structural homology. In keeping with …

α-Synuclein is a small neuronal protein enriched at presynaptic termini. It is hypothesized to
play a role in neurotransmitter release and synaptic vesicle cycling, while the formation of α …