The proportions of term or late preterm births after exposure to early antenatal corticosteroids, and outcomes: systematic review and meta-analysis of 1.6 million infants

K Ninan, A Gojic, Y Wang, EV Asztalos, M Beltempo… - bmj, 2023 - bmj.com
Objective To systematically review the proportions of infants with early exposure to antenatal
corticosteroids but born at term or late preterm, and short term and long term outcomes …

European consensus guidelines on the management of respiratory distress syndrome: 2022 update

DG Sweet, VP Carnielli, G Greisen, M Hallman… - Neonatology, 2023 - karger.com
Respiratory distress syndrome (RDS) care pathways evolve slowly as new evidence
emerges. We report the sixth version of “European Guidelines for the Management of RDS” …

Technical Update No. 438: Antenatal Corticosteroids at Late Preterm Gestation

J Liauw, H Foggin, P Socha, J Crane, KS Joseph… - Journal of Obstetrics and …, 2023 - Elsevier
Objective To update recommendations for administration of antenatal corticosteroids in the
late preterm period. Target Population Pregnant individuals at risk of preterm birth from 34 0 …

A comparison of 2 doses of antenatal dexamethasone for the prevention of respiratory distress syndrome: an open-label, noninferiority, pragmatic randomized trial

S Chawanpaiboon, R Chukaew, J Pooliam - American Journal of …, 2024 - Elsevier
Background Antenatal corticosteroids have been used for the prevention of respiratory
complications, intraventricular hemorrhage, necrotizing enterocolitis, and other adverse …

Antenatal corticosteroids: an updated assessment of anticipated benefits and potential risks

AH Jobe, RL Goldenberg, MW Kemp - American Journal of Obstetrics and …, 2024 - Elsevier
Antenatal steroid therapy is increasingly central to the obstetrical management of women at
imminent risk of preterm birth. For women likely to deliver between 24 and 34 weeks' …

The efficacy of antenatal corticosteroids to improve preterm newborn outcomes in low-resource countries: Are we there yet?

S Sultana, JP Vogel… - BJOG: an international …, 2023 - pubmed.ncbi.nlm.nih.gov
The efficacy of antenatal corticosteroids to improve preterm newborn outcomes in low-resource
countries: Are we there yet? The efficacy of antenatal corticosteroids to improve preterm …

[HTML][HTML] The World Health Organization Antenatal CorTicosteroids for Improving Outcomes in preterm Newborns (ACTION-III) Trial: study protocol for a multi-country …

Trials, 2024 - Springer
Background Preterm birth complications are the leading cause of newborn and under-5
mortality. Over 85% of all preterm births occur in the late preterm period, ie between 34 and< …

A physiologically based toxicokinetic model of P-glycoprotein transporter-mediated placenta perfusion of dexamethasone in the pregnant rat

R Du, X Zhao, L Song, H Wang, D Liu… - Food and Chemical …, 2024 - Elsevier
The present dosage of Dexamethasone (DEX) administered to pregnant women may pose a
risk of toxicity to their unborn offspring. We aimed to develop a maternal-fetal physiologically …

Systematic Quantitative Analysis of Fetal Dexamethasone Exposure and Fetal Lung Maturation in Pregnant Animals: Model Informed Dexamethasone Precision Dose …

L Song, J Song, Y Wang, Y Wei, Y Zhao… - ACS Pharmacology & …, 2024 - ACS Publications
Dexamethasone (DEX) was applied in neonatal respiratory distress syndrome treatment of
pregnant women. We established a pharmacokinetics (PK)/pharmacodynamics (PD)/end …

[HTML][HTML] Survival without severe neonatal morbidity after antenatal betamethasone dose reduction: a post hoc analysis of a randomized non-inferiority trial

O Baud, L Sentilhes, M Ursino, M Doret-Dion… - American Journal of …, 2024 - Elsevier
Background Antenatal betamethasone is recommended before preterm delivery to
accelerate fetal lung maturation. However, its optimal dose remains unknown. A 50% dose …